Protein Alignment dom and ino80

DIOPT Version :9

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: XP_004917366.1
• Gene: ino80 / 100127778
• XenbaseID: XB-GENE-957629
• Length: 1547
• Species: Xenopus tropicalis
• Alignment Length: 1882
• Identity: 472/1882 - (25%)
• Similarity: 726/1882 - (38%)
• Gaps: 536/1882 - (28%)

  Fly   442 LRRPQGQNNASSGSAAASGGGGSLTPTPLYTGNGPAALGGSGGLTPGTPTSGSLLSPALGGGSGT 506
            ||:.....|.|..|..:..|   |..|||.    |.|      ..|........:||.||..||
 Frog    35 LRQTSAVFNRSISSDESEDG---LDETPLL----PEA------EDPSLQVKEEPMSPLLGEPSG- 85

  Fly   507 PNSAAQEFSFKAKQEVYVMQRISELQREGLWTERRLPKLQEPSRPKAHWDYLLEEMVWLAADFAQ 571
             :.:....|..|...:...:..||  |...:...:|.|
 Frog    86 -DGSTDLLSVHALNGILKPEPKSE--RGSFYNFSKLKK--------------------------- 120

  Fly   572 ERKWKKNAAKKCAKMVQKYFQDKATAAQRAEKAQELQLKRVASFIAREVKSFWSNVEKLVEYK-- 634
            .|||.||.      ::.:...|..:.::..|:...|..:.:...:            ::.:||
 Frog   121 SRKWLKNI------LLSEDSSDTDSLSEEDEEEFSLSKEELHDML------------RIHKYKKL 167

  Fly   635 HQTK-IEEKRKQALDQHLSFIVDQTEKFSQQ---LVEGMNKSVADTPSLNSS-RLTSPKRESDDD 694
            ||:| :::|.......:.:.::...:.|.:|   .:....|.:.:.....:. :....||..::|
 Frog   168 HQSKYLKDKELHQYQYYSAGLLSTHDPFYEQQRHFLGPRKKKIKEEKKFKAKLKKVKKKRRREED 232

  Fly   695 FRPESGSEDD-------EETIAKAEEDAADVKEEVTALAKESEMDFDDFLN-------------D 739
            .     |||:       .:..||...||.      |.:.|:..:..:. ||             :
 Frog   233 L-----SEDELPRRHHHTKVFAKFSHDAP------TPVGKKKHLTLEQ-LNARRRKVWQMIVKKE 285

  Fly   740 LPPGY----------LENRDKL----MKEEQSSAIKTETPDDSDDSEFEAKEASDDDENTISKQE 790
            ||..|          |.|..||    |:|.:.:||:.:  .:..::...|:..:.:......|.:
 Frog   286 LPKAYKQKVSARNLLLTNSKKLAHQCMREVRRAAIQAQ--KNCKETLPRARRLTKEMSLYWKKYD 348

  Fly   791 EAEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKL--APRDPEL---------DSDD 844
            :.|:|  |:|.. |.||.....:::.:.:.|.:|      |||  .....||         :|..
 Frog   349 KVEKE--HRKRA-EKEALEQRKLDEEMREAKRQQ------RKLNFLITQTELYAHFVSRKRESGP 404

  Fly   845 DSTAVDSTEESEDAATEDEE-------DLSTVKTDTDMEEQD---EQEDGLKSLMA-----DADA 894
            |....:...:.||::::::.       .||.:..|:|..:..   ..|:..:...|     |.||
 Frog   405 DGIQEEILRKLEDSSSQEQVGAGGSYLHLSQMDYDSDYYKSQALKNAEEAFRIHQAQTRSFDEDA 469

  Fly   895 TSGAAGSGSTA----GASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHI 955
            ....|.:...|    ...|....:.|.:....|.:              |.|.:....|:.||..
 Frog   470 KESRAAAQRVAIKLESGFGESYSLANPSIRAGEDI--------------PQPTIFNGKLKGYQLK 520

  Fly   956 GLDWLVTMNERKLNGILADEMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKW 1020
            |::||..:.|:.:|||||||||||||:|:||||||||..:..|||.||:.|:|.:.||..||.::
 Frog   521 GMNWLANLYEQGINGILADEMGLGKTVQSIALLAHLAERENIWGPFLIISPASTLNNWHQEFSRF 585

  Fly  1021 CPGFKILTYYGSQKERKLKRVGW------TKPNAFHVCITSYKLVVQDQQSFRRKKWKYLILDEA 1079
            .|.||:|.|:||..|||:.|..|      |:...|||.||||:|||||.:.|:|.||:|::||||
 Frog   586 VPKFKVLPYWGSPHERKVIRKFWGQKTLYTQEAPFHVVITSYQLVVQDVKYFQRVKWQYMVLDEA 650

  Fly  1080 QNIKNFKSQRWQLLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTG 1144
            |.:|:..|.||::||.|....||||||||:||.:.|||:|:||:||.:|.||.||.||||..:..
 Frog   651 QALKSSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHDEFSEWFSKDIES 715

  Fly  1145 MIEGNMEYNETLITRLHKVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKT 1209
            ..|.....:|..::|||.:::||:|||:||:||.::..|.|.::.|.|:.||:.||:...::...
 Frog   716 HAENKSAIDENQLSRLHMILKPFMLRRIKKDVENELSDKIEILMYCSLTTRQKLLYQALKNKISI 780

  Fly  1210 RETLQT---------GNLLSVINVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIME 1265
            .:.||:         ....|::|::||.||||||..:||.:.|.|||......:...:.:
 Frog   781 DDLLQSSMGTAQQAQNTTSSLMNLVMQFRKVCNHSELFERQETWSPFHFSLRPYQISKFL----- 840

  Fly  1266 YDPFTQINLETLN--------LLLL-----HLEQTM-TAYVSHKSRLLAPPRKLIEDIDTAPLPA 1316
               |...|:..||        ::|.     |::|:: ....|.|....:    .:..||..|
 Frog   841 ---FRHGNINCLNWSRNRWLRVMLSPFAPDHIQQSLFHRNGSDKESCFS----FLRFIDVCP--- 895

  Fly  1317 PRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMRL-------EGSKIMPMRNLLPSGRVLKR 1374
            ....|...|.|:   :..||..:.|.|       |.||       |||:...:.:.| :.|.|
 Frog   896 AEIGNLMLRGHL---ARWLALFLSLKA-------AYRLHNARVWDEGSQSDSLNSYL-TNRSL-- 947

  Fly  1375 VSASINPVNMALKPVVINSVVTTTSSSTTASSPTGALSVLSNSKLLGARSQINAPTPAKVAKTMQ 1439
                |..||.||      |.....||||...     |...|:.:.:..|..
 Frog   948 ----ILWVNFAL------SFPNLHSSSTLQE-----LVFTSHCRPISGRGD-------------- 983

  Fly  1440 DGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVKS 1504
                  |:.....||.  :::.....|...:....:...||||          ||  |:..:.:|
 Frog   984 ------YVLHGRKSGQ--SQVLHCQITQFPSFLYVASPLVTAS----------PI--DIYCNDRS 1028

  Fly  1505 TVQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREA 1569
                     .:.|..|..|...|...|.|:                     ..|..:|.:..:..
 Frog  1029 ---------AEYERREFREGGGPVSRQCLM---------------------FGAPELYADWPKRQ 1063

  Fly  1570 IQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSVC 1634
            :|....:...|              ..:...||||
 Frog  1064 LQFFPASPGGL--------------MTIKPCNGWS------------------------------ 1084

  Fly  1635 APRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMD 1699
                  |:                                      |.||...:..|.|||..:|
 Frog  1085 ------YI--------------------------------------KIPDKESLITDSGKLYALD 1105

  Fly  1700 RLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKRIFCF 1764
            .||.:||.:||||||::|||:|:|:||.::.|..|.|:|||||:::.:|:.::..|.....||.|
 Frog  1106 LLLTRLKSHGHRVLIYSQMTRMIDLLEEYMVYRKHTYMRLDGSSKISERRDMVADFQSRTDIFVF 1170

  Fly  1765 ILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNILKK 1829
            :||||:||:|||||.||||||||||||||:|.||.||.||:|||:.|.:|||:.:.|||..||::
 Frog  1171 LLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQR 1235

  Fly  1830 ANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTMEQ-------SEQDESSQEKSENKDRIVATTTL 1887
            |.:|..:..:.|.||||.....|...:..|...::       ..|:|..|::..||
 Frog  1236 AKEKSEIQRVVISGGNFKPDTLKPKEVVSLLLDDEELEKKLRQRQEEKRQQEETNK--------- 1291

  Fly  1888 SDTPSTVVETEKQSLRAFEHALAAAEDEQDVQATKTAKAEVAADLAEFD-ENIPIATEDPNAEGG 1951
                   |:..|:....:... ...|||.|.:..|.....|...|...| .|:....||
 Frog  1292 -------VKERKRKREKYAEK-KKKEDEVDGRRKKDGGNLVIPFLPSADNSNLSADGED------ 1342

  Fly  1952 PQVELSKADLEMQNLVKQLSPIERYAMRFVEETGAAWTAEQLRAAEAELEAQKREWEANRLAAMH 2016
               .....|..|.      ||....::.....||:
 Frog  1343 ---SFISVDSAMP------SPFSEISISSELHTGS------------------------------ 1368

  Fly  2017 KEEELLKQETEAEEMLTYSRKDSSNQVWISRNTMEQMPMWCPPTPPQDNDNDIYIDYSLSFMYEL 2081
                 :..:..:.:||... .|.|:....||.|                ::...|..|:|  ..|
 Frog  1369 -----IAPDESSNDMLVIV-DDPSSSAQQSRGT----------------NSPASITGSVS--ENL 1409

  Fly  2082 EPIAETDLP-PVYVRKEHKRSRTDAGYDGSRRPNKMRRED------------------------- 2120
            ..|:..:.| ...|.....|.|..||.:.|:......|:.
 Frog  1410 NGISNQETPNSARVNSSRNRGRAKAGANSSKGGKSRSRKSTAGSAAAIAGAMAGAAAASAAAYAA 1474

  Fly  2121 -NYVPPRSLFDRPTPQLARLRRE-------------LKSQRFRGSFKPNMPIPGLKPQLPTK 2168
             .|...:.|......|.:.||..             :.|...:|:.|.|.|| ||.|:.||:
 Frog  1475 YGYNVSKGLPASSPLQTSLLRTSGISDFGPINTSSPINSPLSKGTPKINNPI-GLAPETPTR 1535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727	9/70 (13%)
		ASF1_hist_chap	<674..831	CDD:304562	36/191 (19%)
		FAM176	<824..>868	CDD:291517	11/61 (18%)
		SNF2_N	952..1238	CDD:278600	142/300 (47%)
		DEXDc	969..1108	CDD:238005	81/144 (56%)
		Helicase_C	1692..1806	CDD:278689	66/113 (58%)
ino80	XP_004917366.1	DBINO	270..399	CDD:372790	29/139 (21%)
		PLN03142	349..>827	CDD:215601	181/500 (36%)
		DEXQc_INO80	514..742	CDD:350760	117/227 (52%)
		SF2_C_SNF	1088..1223	CDD:350180	75/134 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D188211at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920