Protein Alignment Pdp1 and TEF

DIOPT Version :10

• Sequence 1: NP_729301.1
• Gene: Pdp1 / 45588
• FlyBaseID: FBgn0016694
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_003207.1
• Gene: TEF / 7008
• HGNCID: 11722
• Length: 303
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 105/237 - (44%)
• Similarity: 140/237 - (59%)
• Gaps: 22/237 - (9%)

  Fly   429 KEEGDIWNVEAQTAFLGPNLWDKTLPYDADLKVTQYADLDEFLSENNIPDGLPGTHLGHSSGL-- 491
            ::|....:..|.:|.|.|.:||||:|||.:....:|.||||||.||.||  ...|||.|:..|
Human    63 EDEAAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIP--ASPTHLAHNLLLPV 125

  Fly   492 ----GHRSDSLGHAAGLS-----------LGLGHITTKRER-SPSPSD--CISPDTLNPPSPAES 538
                |..|.|...|:..|           :.....:.::|| :|||.|  |:..|....|.||:.
Human   126 AELEGKESASSSTASPPSSSTAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNFNPDPADL 190

  Fly   539 TFSFASSGRDFDPRTRAFSDEELKPQPMIKKSRKQFVPDELKDDKYWARRRKNNIAAKRSRDARR 603
            ..|....|..|:||...|::|:|||||||||::|.|||||.||:|||.||:|||:||||||||||
Human   191 VLSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARR 255

  Fly   604 QKENQIAMRARYLEKENATLHQEVEQLKQENMDLRARLSKFQ 645
            .|||||.:||.:|||||..|..||.:|::|....:..:||::
Human   256 LKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYE 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp1	NP_729301.1	NAM-associated	514..609	CDD:464129	56/97 (58%)
		bZIP_HLF	580..639	CDD:269843	37/58 (64%)
		coiled coil	581..639	CDD:269843	36/57 (63%)
TEF	NP_003207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		105/237 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..176		10/43 (23%)
		bZIP_HLF	232..290	CDD:269843	37/57 (65%)
		coiled coil	233..290	CDD:269843	36/56 (64%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	235..255		16/19 (84%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	256..263		5/6 (83%)