Protein Alignment Pdp1 and Hlf

DIOPT Version :10

• Sequence 1: NP_729301.1
• Gene: Pdp1 / 45588
• FlyBaseID: FBgn0016694
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001390914.1
• Gene: Hlf / 217082
• MGIID: 96108
• Length: 296
• Species: Mus musculus
• Alignment Length: 259
• Identity: 121/259 - (46%)
• Similarity: 149/259 - (57%)
• Gaps: 41/259 - (15%)

  Fly   424 PDD---KYKEEGDIWNVEA------QTAFLGPNLWDKTLPYDADLKVTQYADLDEFLSENNIPDG 479
            |:|   |.|::|...:.|:      |:|||||.|||||||||.|....:|.||:||||||.||..
Mouse    36 PEDAFSKEKDKGKKLDDESSSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPS 100

  Fly   480 LPG--THLGHSSGLGHRSDSLGHAAGLS--------------------LGLGHITTKRERSPSPS 522
             |.  .|..|..||...|.:......||                    :..|.:......:|||
Mouse   101 -PSQHDHSPHPPGLQPASSTAPSVMDLSSRATAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSP- 163

  Fly   523 DCISPDTLN-----PPSPAESTFSFASSGRDFDPRTRAFSDEELKPQPMIKKSRKQFVPDELK-D 581
              |.|||:.     .|.||:...|.......||||.|.||:|||||||||||:||.|:||:|| |
Mouse   164 --IDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKQD 226

  Fly   582 DKYWARRRKNNIAAKRSRDARRQKENQIAMRARYLEKENATLHQEVEQLKQENMDLRARLSKFQ 645
            |||||||||||:||||||||||.||||||:||.:|||||:.|.|||..|::|....:..|:|::
Mouse   227 DKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYE 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp1	NP_729301.1	NAM-associated	514..609	CDD:464129	61/100 (61%)
		bZIP_HLF	580..639	CDD:269843	42/59 (71%)
		coiled coil	581..639	CDD:269843	41/57 (72%)
Hlf	NP_001390914.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..76		18/39 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..149		14/57 (25%)
		bZIP_HLF	226..284	CDD:269843	41/57 (72%)
		coiled coil	226..284	CDD:269843	41/57 (72%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	228..248		18/19 (95%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	249..256		5/6 (83%)