Protein Alignment Pdp1 and Nfil3

DIOPT Version :10

• Sequence 1: NP_729301.1
• Gene: Pdp1 / 45588
• FlyBaseID: FBgn0016694
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_059069.1
• Gene: Nfil3 / 18030
• MGIID: 109495
• Length: 462
• Species: Mus musculus
• Alignment Length: 132
• Identity: 43/132 - (32%)
• Similarity: 63/132 - (47%)
• Gaps: 28/132 - (21%)

  Fly   512 TTKRERSPSPSDCISPDTLNPPSPAESTF----SFASSGRDFDPRTRAFSDEEL--------KPQ 564
            |.|:|.:|          |:|.|.::...    :.|....|.      .|.|:|        |.:
Mouse     8 TIKKEPAP----------LDPTSSSDKMLLLNSALAEVAEDL------ASGEDLLLNEGSMGKNK 56

  Fly   565 PMIKKSRKQFVPDELKDDKYWARRRKNNIAAKRSRDARRQKENQIAMRARYLEKENATLHQEVEQ 629
            ....:.:::|:|||.||..||.:|||||.||||||:.||..:..:..:...|.:|||||..|:..
Mouse    57 SSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLS 121

  Fly   630 LK 631
            ||
Mouse   122 LK 123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp1	NP_729301.1	NAM-associated	514..609	CDD:464129	33/106 (31%)
		bZIP_HLF	580..639	CDD:269843	26/52 (50%)
		coiled coil	581..639	CDD:269843	25/51 (49%)
Nfil3	NP_059069.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		7/23 (30%)
		bZIP_NFIL3	72..131	CDD:269842	26/52 (50%)
		coiled coil	73..131	CDD:269842	25/51 (49%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	79..95		11/15 (73%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	99..106		0/6 (0%)
		Vert_IL3-reg_TF	130..461	CDD:368956
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..214
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..298
		Necessary for transcriptional repression and sufficient for interaction with PER2. /evidence=ECO:0000269|PubMed:17274955	281..420