DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pdp1 and DBP

DIOPT Version :9

Sequence 1:NP_729301.1 Gene:Pdp1 / 45588 FlyBaseID:FBgn0016694 Length:647 Species:Drosophila melanogaster
Sequence 2:NP_001343.2 Gene:DBP / 1628 HGNCID:2697 Length:325 Species:Homo sapiens


Alignment Length:236 Identity:101/236 - (42%)
Similarity:129/236 - (54%) Gaps:50/236 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   444 LGPNLWDKTLPYDADLKVTQYADLDEFLSENNIP-----------------------------DG 479
            |.|.||::|||: .|:   :|.|||.||.|:.:|                             ..
Human   100 LAPLLWERTLPF-GDV---EYVDLDAFLLEHGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSA 160

  Fly   480 LPGTHLGHSSGLGHRSDSLGHAAGLSLGLGHITTKRERSPSPSDCISPDTLN-----PPSPAEST 539
            .|.:..||:........:.||.|||        |.|: :|||.|   |||:.     .|.||:..
Human   161 SPRSSPGHAPARAALGTASGHRAGL--------TSRD-TPSPVD---PDTVEVLMTFEPDPADLA 213

  Fly   540 FSFASSGRDFDPRTRAFSDEELKPQPMIKKSRKQFVPDELKDDKYWARRRKNNIAAKRSRDARRQ 604
            .|.......||||...||:|||||||::||:||..||:|.||:|||:||.|||.||||||||||.
Human   214 LSSIPGHETFDPRRHRFSEEELKPQPIMKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRL 278

  Fly   605 KENQIAMRARYLEKENATLHQEVEQLKQENMDLRARLSKFQ 645
            |||||::||.:||||||.|.|||..::||....||.||::|
Human   279 KENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQ 319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pdp1NP_729301.1 bZIP_HLF 580..639 CDD:269843 39/58 (67%)
coiled coil 581..639 CDD:269843 38/57 (67%)
DBPNP_001343.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..99
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..200 18/84 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 229..255 16/25 (64%)
bZIP_HLF 254..313 CDD:269843 39/58 (67%)
Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 257..279 18/21 (86%)
coiled coil 258..309 CDD:269843 36/50 (72%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 283..297 9/13 (69%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165151882
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3119
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1023460at2759
OrthoFinder 1 1.000 - - FOG0000980
OrthoInspector 1 1.000 - - otm40600
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR11988
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5193
SonicParanoid 1 1.000 - - X901
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
109.840

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