Protein Alignment Pdp1 and Cebpd

DIOPT Version :10

• Sequence 1: NP_729301.1
• Gene: Pdp1 / 45588
• FlyBaseID: FBgn0016694
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_031705.3
• Gene: Cebpd / 12609
• MGIID: 103573
• Length: 268
• Species: Mus musculus
• Alignment Length: 951
• Identity: 179/951 - (18%)
• Similarity: 318/951 - (33%)
• Gaps: 279/951 - (29%)

  Fly    25 SVSNRS-NKSSDAEPS----PSDSLRSQDNSEFKPFLGLSNWLSSVTHRKSPSSSNATNSKEDDT 84
            :|:.|| |......||    ||::||       :.|||.....||::..||.|::|...|..||:
Mouse   114 NVALRSKNPILKERPSSAIYPSETLR-------QSFLGSRKGRSSLSLNKSVSTNNIAGSLNDDS 171

  Fly    85 TMEHGGPVGSESGMQGLGSSSNSKDPEVEEEYQIQLALELSAREDPEAAQIEAMKQFSLGSRPSA 149
                  |:|....:.....|.|.::..:..|         |..::.|......|::.....:..|
Mouse   172 ------PIGLRRILSHSTDSLNFRNRAMSME---------SLNDEGETYYTSMMEELERDGKDFA 221

  Fly   150 PENTPAELMAYRYWNYNCLGYDD-----------KIVDGFYDLCGVMNESSLKRIPPLVD----- 198
            .::          |:   |..|.           |..|..|:|  :..|.:..|...:::
Mouse   222 ADS----------WS---LAVDSSYLQSQRKDVIKRQDVIYEL--IQTEFNHVRTLRIMEGVFRR 271

  Fly   199 --LQGTLVSDGVTW-------DAVLVNSSKDSNLLRLEQMALDIAAKSKSASSSGFVNSELVRQL 254
              |:..::..||..       ..:|::::..|.||:         .:|.|.:|:...|..:.:..
Mouse   272 GMLEEVMMEMGVVHAIFPCLDQLLLIHTNFLSQLLQ---------RRSNSLASNSNRNFTIQKLG 327

  Fly   255 AVLVADYMGGPVLDPDSTLRAWWSLSYSLKATLRSMVLPLGSLTIGLARH-RAL-LFKVLCDSVG 317
            .:||..:.|....|                  :|...:...|      || :|: |:|.|.
Mouse   328 DILVEQFSGQNAED------------------MRKCYVEFCS------RHLKAVKLYKELL---- 364

  Fly   318 VPCRIVKGQQYTGSDDVAMNSIKTDDGREYIVDLMGDPGTLIPADAAGLQMDFDDSVYSASPRDV 382
              .|..:.||:...  |:..|:....|.:..:.|:....|..|   ..:|...|::    ...:.
Mouse   365 --ARDKRFQQFIRR--VSRGSLLRRHGVQECILLVTQRITKYP---VLMQRILDNT----KGNEE 418

  Fly   383 DSSHVASSSS-------GVESSIEEHTESWSAEHRSRTKGSREENQSAGGGDLMIPNIREAVGSQ 440
            :|..:|.|.:       .|:..::|...:...:........|.|.:..|||
Mouse   419 ESKSLAQSLTLIRELLCSVDQQVQELERAQRLQEIQSRLDPRAETKVKGGG-------------- 469

  Fly   441 KAPVQHLSSKPTHSFTHARSPSWTEGVSSPAGRRMK------VKDVSQYMIDAAKEN--PQLAQK 497
               |.|.:........|..:..|    .:..|.|:|      :.||..:|.:..::.  |.|.:.
Mouse   470 ---VFHGAELLRRGLIHEGALLW----KTAQGSRLKDVHVLLMTDVLVFMQEKDQKYVFPTLDKP 527

  Fly   498 ----LHDVLLESGVVAPRNLFSEVYSESMEATGEIKSVAESNDEKGKDFGTIQQGRNQSNLGPVR 558
                |.::::.......|.:|...:|...|.   .:..|.|.|::......|||  ..||. |.|
Mouse   528 SVLCLQNLIVRDIANQQRGMFLISHSTPPEM---YELHAASKDDRNTWMKIIQQ--TVSNC-PSR 586

  Fly   559 FLPPLPRPQSKAITH----DLREHSGSGLGHLSEHCNI--------DGHSDSSHSETSTDYPRNV 611
            ...||...:.||:..    |:::.....|..|.|...:        .|.:.:..:.:...:..:.
Mouse   587 EDFPLIETEDKALLRRLRADIQQKDREVLELLQERVTLFSDLVEATGGQNVTVPTNSRNIFRADT 651

  Fly   612 PVAVAAAAVVASSMVVAAAKSANSDSSTLE------LSAAAAAAVMATAAAVSRQFELDSLSNGD 670
            |.|..|..::..::|.....|....||.:|      |:..|....:.:..|...:..:    ||.
Mouse   652 PYAPQAEKLLNEAIVEVDRLSDVLLSSCIERPQSCRLNGEATEVQLTSKTADKERISV----NGT 712

  Fly   671 AGSGGLHGVDSGGERISDRSIGNESSKSDAAIDDVAECEILWEEITVAERIGLGSYGEVYRGDWH 735
            ..:.|....|..|.::.|:.:..|            .|:.|   :.::.::             |
Mouse   713 YDTNGPSNKDRNGNQLLDKLLNEE------------VCQRL---VNLSTQL-------------H 749

  Fly   736 GTAVAVKKFIDQDITGEALEEFRSEVRMMRRLRHPNIVLFMGAVTRPPNLSIVTEFLPRGSL--Y 798
            ....||   |.||       .| .||.|.:.                   |..|...|.||:  :
Mouse   750 SIQAAV---IRQD-------SF-LEVYMQKE-------------------SSPTTGTPAGSVGDF 784

  Fly   799 RLIHRPNNQLD-ERKRLRMALDAARGMNYLHSCNPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRM 862
            ..:.|..|||. |..||:.|.|        .:.|.:.|....|..    ||            |.
Mouse   785 AELQRKYNQLQGEMIRLQAAQD--------KTSNGIPVQDSAKGQ----DK------------RE 825

  Fly   863 KVSTYLSSKSTAGTAE----WMAPEV-----LRNEPADEKC 894
            |:::..|::...|..|    .|:|..     |::.|.:.:|
Mouse   826 KLTSKESTEQLDGKQEEGKMVMSPRADSPRDLQDIPEESEC 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp1	NP_729301.1	NAM-associated	514..609	CDD:464129	22/106 (21%)
		bZIP_HLF	580..639	CDD:269843	10/66 (15%)
		coiled coil	581..639	CDD:269843	10/65 (15%)
Cebpd	NP_031705.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	97..132		6/17 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	152..219		15/81 (19%)
		bZIP_CEBPD	188..252	CDD:269862	12/87 (14%)
		coiled coil	191..249	CDD:269862	10/79 (13%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	195..222		4/35 (11%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	226..254		6/32 (19%)