Protein Alignment Pdp1 and CEBPE

DIOPT Version :10

• Sequence 1: NP_729301.1
• Gene: Pdp1 / 45588
• FlyBaseID: FBgn0016694
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001796.2
• Gene: CEBPE / 1053
• HGNCID: 1836
• Length: 281
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 50/245 - (20%)
• Similarity: 73/245 - (29%)
• Gaps: 97/245 - (39%)

  Fly   486 GHSSGLGHRSDSLGHAAGLSLGLGHITTKRER--------SPSPSD------------------- 523
            |..:|.|...|...|.|.:.|. .:|.:..|:        .|:|..
Human    22 GGRAGPGELGDMCEHEASIDLS-AYIESGEEQLLSDLFAVKPAPEARGLKGPGTPAFPHYLPPDP 85

  Fly   524 ---CISPDTLNPPSPAESTFSFASSGRDFDPRTRAFSDEELKPQ--------------------- 564
               ...|.|..|...|.....::|.| .:|||..|..:|...|:
Human    86 RPFAYPPHTFGPDRKALGPGIYSSPG-SYDPRAVAVKEEPRGPEGSRAASRGSYNPLQYQVAHCG 149

  Fly   565 --------------------------------PMIK---------KSRKQFVPDELKDDKYWARR 588
                                            |::|         |.:|....|.|   :|..||
Human   150 QTAMHLPPTLAAPGQPLRVLKAPLATAAPPCSPLLKAPSPAGPLHKGKKAVNKDSL---EYRLRR 211

  Fly   589 RKNNIAAKRSRDARRQKENQIAMRARYLEKENATLHQEVEQLKQENMDLR 638
            .:||||.::|||..:::..:...:......||..|...||||.||...||
Human   212 ERNNIAVRKSRDKAKRRILETQQKVLEYMAENERLRSRVEQLTQELDTLR 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp1	NP_729301.1	NAM-associated	514..609	CDD:464129	31/186 (17%)
		bZIP_HLF	580..639	CDD:269843	21/59 (36%)
		coiled coil	581..639	CDD:269843	21/58 (36%)
CEBPE	NP_001796.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		3/7 (43%)
		PHA03247	<62..192	CDD:223021	16/130 (12%)
		bZIP_CEBPE	202..262	CDD:269863	23/63 (37%)
		coiled coil	204..262	CDD:269863	22/61 (36%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	208..228		9/19 (47%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	230..237		0/6 (0%)