DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nompA and cutl-18

DIOPT Version :9

Sequence 1:	NP_524831.2	Gene:	nompA / 45587	FlyBaseID:	FBgn0016047	Length:	1557	Species:	Drosophila melanogaster
Sequence 2:	NP_505875.2	Gene:	cutl-18 / 179565	WormBaseID:	WBGene00009830	Length:	801	Species:	Caenorhabditis elegans

Alignment Length:	321	Identity:	66/321 - (20%)
Similarity:	109/321 - (33%)	Gaps:	107/321 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RKGIHVLLTTLVVSLSLSKINGQTTCKN---GLGRVLYERLPNQQLQGYDDDVVRDTAPPFRVLE 65
            ::.:|.|....:|:....:|.|::...|   |||                           :.:|
Worm   180 KEAVHCLNAFKMVAFDAIEIRGESRIFNGSDGLG---------------------------KCME 217

  Fly    66 KCQDLCLRDRSGSNNLVRTCTSFDFQPGSRITSFGGNSEYEESLCYLTSEQAGPEGIGSLMLVPN 130
            ||:| |  |....|.....|.|....|..::..| .|.||:                    ::.|
Worm   218 KCKD-C--DVVMYNEGFSECYSVWNDPSGQLLDF-VNDEYQ--------------------ILTN 258

  Fly   131 SVHFNEICLTSSRPERECPSRR--YVFERHPRKKLKLPISDIKEITAANRSDCEDKCLNEFSFVC 193
            :..:.         ::.|.||.  |:...:|.:.||              |:|.:||  ..|..|
Worm   259 ACSYQ---------KKTCNSRNSLYISYSNPDESLK--------------SECLEKC--TMSEEC 298

  Fly   194 RSANFDSTMRSCTLSRFTRRTHPELMEDDPNSDYLENTCLNAERRCDGLAVF------VKEENKR 252
            |.|.....|.:|.:|| .|...|.|         .:..|.:.....||.|:.      .|.||.:
Worm   299 RFAYQSKDMNNCLISR-RRMALPML---------AQKICADVNDLSDGSAILFDELGGCKNENGQ 353

  Fly   253 LGGPFEVDIFNNMTLEECQTMCLRAEKYFCRSVEFDDQSKQCILSEEDSISQKDDISISSS 313
            |       |..::.|.:|..:|.......|.|:.: .:|:.|.|  .|...:.|:.:.:.|
Worm   354 L-------ISKDLELHQCMQLCATHPTRSCESISY-TKSRDCYL--HDGAVETDNENTNCS 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nompA	NP_524831.2	PAN_AP_HGF	150..231	CDD:238532	21/82 (26%)
		PAN_AP_HGF	244..>303	CDD:238532	14/64 (22%)
		PAN_AP_HGF	349..424	CDD:238532
		PAN_AP_HGF	914..1011	CDD:238532
		ZP	1025..1264	CDD:214579
cutl-18	NP_505875.2	PAN_AP_HGF	105..177	CDD:238532
		PAN_AP	187..258	CDD:214680	21/121 (17%)
		ZP	474..719	CDD:214579
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.970