DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nompA and noah-1

DIOPT Version :9

Sequence 1:	NP_524831.2	Gene:	nompA / 45587	FlyBaseID:	FBgn0016047	Length:	1557	Species:	Drosophila melanogaster
Sequence 2:	NP_001250022.1	Gene:	noah-1 / 172261	WormBaseID:	WBGene00016422	Length:	1052	Species:	Caenorhabditis elegans

Alignment Length:	424	Identity:	102/424 - (24%)
Similarity:	161/424 - (37%)	Gaps:	104/424 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 YERLPNQQLQGYDDDVVRDTAPPFRVLEKCQDLCLRDRSGSNNLVRTCTSFDFQPGSRITSFGGN 102
            |..:..:||:...|.::...      |:.||.||.:..|.|:|.. .|.||.:...:|
Worm   203 YIAVEGKQLKNELDRIINVD------LDSCQALCTQRLSISSNDF-NCKSFMYNNKTR------- 253

  Fly   103 SEYEESLCYLTSEQAGPEGIGSLMLVPNSVHFNEICLTSSRPERECPSRRYVFERHPRKKL---- 163
                  .|.|..|::.|.|...|:......:|.:.|..|....|..||    |:|.|:..|
Worm   254 ------TCILADERSKPLGRADLIATEGFTYFEKKCFASPNTCRNVPS----FKRVPQMILVGFA 308

  Fly   164 KLPISDIKEITAANRSDCEDKCLNE-----FSFVCRSANFDSTMRSCTLSRFTRRTHPELMEDDP 223
            ...:.::..:|.     |.|:|.|.     ..|||:|..:....:.|.|:..||.:.|||...:.
Worm   309 AFVMENVPSVTM-----CLDQCTNPPPETGDGFVCKSVMYYYNEQECILNSETRESKPELFIPEG 368

  Fly   224 NS---DYLENTCLNAERRC-DGLAV-FVKEENKRL-GGPFEVDIFNNMT---LEECQTMC--LRA 277
            ..   ||.:.||...:.:| .|..: .::..|..| .|..|:.:.....   ::||...|  |..
Worm   369 EEFLVDYFDITCHLKQEKCPTGQHLKAIRTINAALPEGESELHVLKASAAKGIKECVAKCFGLAP 433

  Fly   278 EKYFCRSVEFDDQSKQCIL-------SEEDSISQKDDISISSSPTHHFYDLVCLDNQRANDYPDN 335
            ||  |||..:|.::|.|.|       :.:..:.|..|:          |||.||..:  ||
Worm   434 EK--CRSFNYDKKTKSCDLLYLDGHNTLQPQVRQGVDL----------YDLHCLAVE--ND---- 480

  Fly   336 SVTSHLFSSGRRPDTAFQRYRNSRLGGEFHSEITGRSLSECLDECLRQTSFQCRSAVYSDRFRTC 400
                   .|..:.|..|.||.:::..|.........||:.||:.|....              ||
Worm   481 -------CSANKDDALFSRYLHTKQRGIPAKVYKVVSLNSCLEVCAGNP--------------TC 524

  Fly   401 RLSRYNQKDGMRIIYDA---------DYDYYENL 425
            ..:.||::.|...::||         ..|:|:||
Worm   525 AGANYNRRLGDCTLFDAIDDDAEINEHTDFYKNL 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nompA	NP_524831.2	PAN_AP_HGF	150..231	CDD:238532	23/92 (25%)
		PAN_AP_HGF	244..>303	CDD:238532	17/72 (24%)
		PAN_AP_HGF	349..424	CDD:238532	19/83 (23%)
		PAN_AP_HGF	914..1011	CDD:238532
		ZP	1025..1264	CDD:214579
noah-1	NP_001250022.1	PAN_AP_HGF	107..189	CDD:238532
		PAN_AP_HGF	201..282	CDD:238532	23/98 (23%)
		PAN_AP_HGF	295..379	CDD:238532	23/92 (25%)
		PAN_AP_HGF	391..473	CDD:238532	21/93 (23%)
		PAN_APPLE	485..557	CDD:294081	19/85 (22%)
		Zona_pellucida	<818..920	CDD:278526
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010