Protein Alignment nompA and nompA

DIOPT Version :10

• Sequence 1: NP_524831.2
• Gene: nompA / 45587
• FlyBaseID: FBgn0016047
• Length: 1557
• Species: Drosophila melanogaster
• Sequence 2: XP_061501920.1
• Gene: nompA / 1270003
• VectorBaseID: AGAMI1_004906
• Length: 1499
• Species: Anopheles gambiae
• Alignment Length: 1672
• Identity: 938/1672 - (56%)
• Similarity: 1075/1672 - (64%)
• Gaps: 328/1672 - (19%)

  Fly    11 LTTLVVSLSLSKINGQTTCKNGLGRVLYERLPNQQLQGYDDDVVRDTAPPFRVLEKCQDLCLRDR 75
            :|.||:....:.:.|||||.||.|||||||||||||||:|||||||:||||||||||||||||||
Mosquito    14 VTVLVLLARFALVLGQTTCNNGQGRVLYERLPNQQLQGFDDDVVRDSAPPFRVLEKCQDLCLRDR 78

  Fly    76 SGSNNLVRTCTSFDFQPGSRITSFGGNSEYEESLCYLTSEQAGPEGIGSLMLVPNSVHFNEICLT 140
            :.||||.|.||||||||||||.||.|:.|||||.||||.|||.|||||:||||||||||.|:|:|
Mosquito    79 TASNNLGRACTSFDFQPGSRIASFSGSVEYEESTCYLTREQAAPEGIGNLMLVPNSVHFTEVCIT 143

  Fly   141 SSRPERECPSRRYVFERHPRKKLKLPISDIKEITAANRSDCEDKCLNEFSFVCRSANFDSTMRSC 205
            ||||:|||||||||||||||||||||:|||||:||||||||||||||||||||||||:|||:|||
Mosquito   144 SSRPDRECPSRRYVFERHPRKKLKLPVSDIKEVTAANRSDCEDKCLNEFSFVCRSANYDSTLRSC 208

  Fly   206 TLSRFTRRTHPELMEDDPNSDYLENTCLNAERRCDGLAVFVKEENKRLGGPFEVDIFNNMTLEEC 270
            .:|||||||||||:|||||||||||||||||||||||.|:||||||||||||||:||||||||||
Mosquito   209 AMSRFTRRTHPELLEDDPNSDYLENTCLNAERRCDGLIVYVKEENKRLGGPFEVEIFNNMTLEEC 273

  Fly   271 QTMCLRAEKYFCRSVEFDDQSKQCILSEEDSISQKDDISISSSPTHHFYDLVCLDNQRANDYPDN 335
            |::|||||||||||:|||||:||||||||||:|||||:||||||||||||||||||||..:||||
Mosquito   274 QSLCLRAEKYFCRSIEFDDQTKQCILSEEDSVSQKDDLSISSSPTHHFYDLVCLDNQRGAEYPDN 338

  Fly   336 SVTSHLFSSGRRPDTAFQRYRNSRLGGEFHSEITGRSLSECLDECLRQTSFQCRSAVYSDRFRTC 400
            |||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   339 SVTSHLFASGRRPDTAFQRYRNSRLGGEFHSEITGRSLSECLDECLRQTSFQCRSAVYSDRFRTC 403

  Fly   401 RLSRYNQKDGMRIIYDADYDYYENLMLNVVGGGADGDGGGHGGSSDGKRPGDQSGSNWRQPNKHD 465
            |||||||:||||||||||||||||||.::|||..|...|         ||   ..::||.
Mosquito   404 RLSRYNQRDGMRIIYDADYDYYENLMPHLVGGDTDTTNG---------RP---DPTDWRP----- 451

  Fly   466 DRYGSGGSSVGGGSHGGTGSGGSRLPPGEGVDYGRPYDRYPDIAGNEYDRNPYGGDRDRDRYPPD 530
                                                               ||||||||||.|.|
Mosquito   452 ---------------------------------------------------PYGGDRDRDRVPDD 465

  Fly   531 R-------YGSRYPT------GGDGI--GYNRPYDRFPDDYDRYPAGAGVN------GDRDRERD 574
            |       .|.|||.      ||:..  || .|.||:|...||||.|.|.:      ||.|
Mosquito   466 RIPPGRYPQGDRYPMGSRPEYGGEPFPGGY-PPTDRYPGSTDRYPVGPGTDRYPSGGGDYD---- 525

  Fly   575 RDRYPVVGDRDRYPGAVDR----DRYPGVRDRD--------RYPEP---------YPPERYADRY 618
             .|||.|.| :|:||  ||    |||||.||.|        |||.|         ||.:   .||
Mosquito   526 -GRYPPVYD-NRFPG--DRYGPTDRYPGDRDPDPMYPGGPMRYPPPPPLPPPGSGYPSD---SRY 583

  Fly   619 G-----DRRYPERERDRDRDRLPYRPLPYPGINDNSLPSDLPHTRPYPTDDDAPFRPYGYGGGRY 678
            .     |.|||       .||.|.....||. .|:..|:|   .|..||..||        ||||
Mosquito   584 PPPMPMDSRYP-------MDRYPPSDSRYPA-PDSRYPAD---ARYPPTQPDA--------GGRY 629

  Fly   679 ------GENRY----EGRYPP----RFPPSRERDPVGGYTGRDAPDSIFPDRRYRPSSMDSPRYP 729
                  ...||    .|||||    |:||..:| |...|.....|.:.:|..:|.|....|..||
Mosquito   630 PPGPAPDSGRYPPPESGRYPPPDSGRYPPPVQR-PDSRYPVMAPPATRYPPPQYMPHMYGSAVYP 693

  Fly   730 YLPDSRGPPGR-YDDIVHSARRPEPDSAK-----RYPPA-----PIAPTGSSSKYASTPNRFPVG 783
            .:| ||.||.| |....:    |.|..|:     |||||     |:.|.|:..:|.::||..|
Mosquito   694 VVP-SRAPPNRGYGPDPY----PAPPGARPIDNNRYPPAPDARYPLEPVGAQGRYPTSPNVSP-- 751

  Fly   784 NDRYPIDIYKYGNRPGPNDLGRRPGLERPPPPFYDYDYEERYG---DRYGPY------------- 832
                   .:||...||....|..|         |...||.:.|   ||||.|
Mosquito   752 -------FHKYMTGPGRPSAGYDP---------YMGGYEPQRGYVDDRYGGYYPSGGGRLPPPLP 800

  Fly   833 ---------DREYDGPPGRRPPSGGPYGRYDSPFNRPYG--GNGLDDRPLPLPGLGLSHPPTPYG 886
                     ||.|..|.....|.||.|     ||..|||  |.|.|:..
Mosquito   801 PPMPAFPDRDRGYRRPAVGMAPDGGGY-----PFEIPYGPSGTGYDNTL---------------- 844

  Fly   887 GGGAGHVGVGVGVNSGPPRPPITRCEESDNFKQIAARHKMRRHFVRRALIVPSLIQCERECIESR 951
            |||.|..|.      ||.||..|||:.:|.|||:||:.|||:.::||.:..|||..|::||..:|
Mosquito   845 GGGDGFGGY------GPQRPYETRCDNTDTFKQVAAKRKMRKQYIRRVINAPSLGICQQECAGAR 903

  Fly   952 DFVCRSFNYRDSAASGYEDRDRDRDRDSPNCELSDRDSRELDIHDPGTFDASNYDFYERSIGRS- 1015
            ||:||||||||||.  ||...        ||||||||||:|::.....|::.:.|:|||:.||.
Mosquito   904 DFMCRSFNYRDSAP--YETEG--------NCELSDRDSRDLEVPSTQMFESDSADYYERTPGRGG 958

  Fly  1016 -DGECMDVTQTCNEEGMEFTIRTPEGFLGRIYTYGFYDRCFFRGNGGTVNVLRLSGPQGYPDCGT 1079
             ..||:||.|.|||:|||||:||||||:||||.||||||||||||||||||||:|||||||:|||
Mosquito   959 PHDECLDVGQVCNEDGMEFTLRTPEGFVGRIYAYGFYDRCFFRGNGGTVNVLRISGPQGYPECGT 1023

  Fly  1080 QRYGDTLTNIVVVQFSDNVQTSRDKRYNLTCIFRGPGEAVVSSGYIGAG------SGSPIPIEYL 1138
            ||||||:|||:||||||||||.||||:||||:|||||||||:|||||||      ||||||||||
Mosquito  1024 QRYGDTMTNIIVVQFSDNVQTGRDKRFNLTCMFRGPGEAVVTSGYIGAGFQSIDRSGSPIPIEYL 1088

  Fly  1139 PAENTLSSKVRLSILYQGRPTTTIAVGDPLTFRLEAQDGYNHVTDIFATNVVARDPYSGRSIQLI 1203
            ||||::|:||||.||||||||||||||||||||||:||||:|.||||||||||||||||||:|||
Mosquito  1089 PAENSMSNKVRLMILYQGRPTTTIAVGDPLTFRLESQDGYSHATDIFATNVVARDPYSGRSVQLI 1153

  Fly  1204 DRFGCPVDPFVFPELDKLRDGDTLEARFNAFKIPESNFLVFEATVRSCREGCQPAYCPGPAGRQE 1268
            |.:|||||..|||||.:.||.|.|||||||||||||||||||||||:||.||||||||||:||.|
Mosquito  1154 DNYGCPVDSLVFPELGRSRDNDALEARFNAFKIPESNFLVFEATVRTCRGGCQPAYCPGPSGRSE 1218

  Fly  1269 PSFGRRRRSL-NTTE-IPEPEALALEGSSQLEASTLDEVTVVNSTTVSATLGQVPLNETQLGEKT 1331
            ||||||:||| |.|| |...|.|........:... |||::||.|.|         ||.....||
Mosquito  1219 PSFGRRKRSLENGTETIGTAEPLVAANPDPADDED-DEVSIVNGTMV---------NENATSAKT 1273

  Fly  1332 KE---------------TEEPEQVREMIE--------VFETREEIEKESYPRKLVAPVETVCMTP 1373
            ::               ||.|||||||||        ||::|||:::::..||:|||:|:||:|.
Mosquito  1274 RDASGDTITAEADTTSPTEMPEQVREMIESRYFRPLQVFQSREEMQQDTVARKMVAPIESVCLTH 1338

  Fly  1374 AEYHGLITAIILLMILLFSITLVAGLGYRRYWKSISKNRLVDRHSPIHSLGHSHSSIRTHERFTE 1438
            |||:|||:|:|||:|||.|||..||:.||.|||...|||.:||.||::|..
Mosquito  1339 AEYYGLISAVILLIILLISITFAAGIVYRSYWKVFIKNRTLDRSSPVNSFS-------------- 1389

  Fly  1439 IGHMPNLNGGGGGAAAGTGGGANQSASNRASNA----FRT-NMSMFGGSLHKTFATGNLARMCQL 1498
                |:.....||:.....|.|:.:|| |...|    .|| .:|:||..|.||||||||:||||:
Mosquito  1390 ----PSALHNAGGSQFEASGRAHSTAS-RGGGAGTPHVRTPGVSLFGSGLQKTFATGNLSRMCQI 1449

  Fly  1499 PVINPMRSTNQSSHQFEDPSEPIYTDPSLFERSRQVADHSVTHPQNE 1545
            ||:||:........:|:|||||||||||||||||.:  .|:...|.|
Mosquito  1450 PVMNPLSRAGAPKSEFDDPSEPIYTDPSLFERSRSL--RSIAVDQTE 1494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nompA	NP_524831.2	PAN_AP_HGF	150..231	CDD:238532	73/80 (91%)
		PAN_AP_HGF	244..>303	CDD:238532	52/58 (90%)
		PAN_AP_HGF	349..424	CDD:238532	73/74 (99%)
		PHA03247	<579..907	CDD:223021	126/405 (31%)
		PAN_AP_HGF	914..1011	CDD:238532	47/96 (49%)
		ZP	1025..1264	CDD:214579	206/244 (84%)
nompA	XP_061501920.1	None