DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Faa and Fahd2a

DIOPT Version :9

Sequence 1:	NP_524830.2	Gene:	Faa / 45577	FlyBaseID:	FBgn0016013	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001128306.1	Gene:	Fahd2a / 296131	RGDID:	1563674	Length:	313	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	91/392 - (23%)
Similarity:	129/392 - (32%)	Gaps:	157/392 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 QVQK------------SLQAETLNE-LMGL---------DFEAWDVVRSQTQKLLTKGSELDHNV 97
            ||||            ..||..|.| .:||         |...:|....:|.....:..|...:|
  Rat    15 QVQKRPCQPCRNMRLVQFQAPHLEEPHVGLESGIGGGVVDLNTFDPALPKTMVQFLERGETALSV 79

  Fly    98 DLKAVS----IVPQSEIKLHLPAQIGD--------YTDFYSSIHHATNVGIMFRGPDNALMPNWR 150
            ..:|::    ::|:|::....|....|        |.|      |.....:  |.|.|
  Rat    80 ARRALAAQLPLIPRSQVTFLAPVTRPDKVICVGLNYAD------HCQEQNV--RVPKN------- 129

  Fly   151 HLPVGYHGRASSVVVSGTPIRRPLGQTFPDGAEKPVFGACKLLDFELEMAFFIGGKGNQLGEPIR 215
              |:.:...:||:|.....|..|     |:..|         :|:|:|||..||.||..    |:
  Rat   130 --PIIFSKFSSSIVGPYDSIILP-----PESKE---------VDWEVEMAVVIGKKGKH----IK 174

  Fly   216 VDEAWKNVFGFTLMNDWSARDIQ-----KW-------EYVPLGPFTAKNLGTTISPWVVPTAALK 268
            ..:....|.|||:.:|.||||.|     :|       .:.|||                |....|
  Rat   175 ATDVMAYVAGFTVAHDVSARDWQMRNGKQWLLGKTFDTFCPLG----------------PALVTK 223

  Fly   269 PFVLDNFPQEPEVLPYLRQNIPFNFDINLEVSLKPADQNEALISKSNFKHLYWTPLQQIA--HHT 331
            ..:.|                |.|..|:..|       |..::..||...:.:.....||  ...
  Rat   224 DTIAD----------------PHNLKISCRV-------NGEIVQSSNTNQMVFKTEDLIAWVSQF 265

  Fly   332 VTGCNLRPGDLMASGTISGETPDSYGSLLELCWKGTKTLELPG-GKTRK---FLQDFDEVIIRGH 392
            ||   |.|||::.:|     ||                   || |..||   ||:..|||    .
  Rat   266 VT---LYPGDILLTG-----TP-------------------PGVGMFRKPPVFLKKGDEV----Q 299

  Fly   393 CE 394
            ||
  Rat   300 CE 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Faa	NP_524830.2	PLN02856	1..414	CDD:215461	91/392 (23%)
		FAA_hydrolase_N	17..115	CDD:286391	18/85 (21%)
		FAA_hydrolase	121..409	CDD:279845	71/292 (24%)
Fahd2a	NP_001128306.1	MhpD	48..313	CDD:223257	81/359 (23%)
Fahd2a	NP_001128306.1	FAA_hydrolase	109..312	CDD:279845	71/298 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0179
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810