Protein Alignment Faa and FAH

DIOPT Version :10

• Sequence 1: NP_524830.2
• Gene: Faa / 45577
• FlyBaseID: FBgn0016013
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_000128.1
• Gene: FAH / 2184
• HGNCID: 3579
• Length: 419
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 251/415 - (60%)
• Similarity: 305/415 - (73%)
• Gaps: 7/415 - (1%)

  Fly     4 SFVPVPENSDFPLENLPYAVFSTENNKVHRICVAIGEHVLDLKAVSQLFPFQV----QKSLQAET 64
            ||:||.|:||||:.||||.||||..:...||.||||:.:|||..:..||...|    |......|
Human     2 SFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPT 66

  Fly    65 LNELMGLDFEAWDVVRSQTQKLLT-KGSELDHNVDLKAVSIVPQSEIKLHLPAQIGDYTDFYSSI 128
            ||..|||...||...|...|.||: ..:.|..:.:|:..:.:.|:...:||||.||||||||||.
Human    67 LNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSR 131

  Fly   129 HHATNVGIMFRGPDNALMPNWRHLPVGYHGRASSVVVSGTPIRRPLGQTFPDGAEKPVFGACKLL 193
            .||||||||||..:|||||||.|||||||||||||||||||||||:||..||.::.||:||||||
Human   132 QHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLL 196

  Fly   194 DFELEMAFFIGGKGNQLGEPIRVDEAWKNVFGFTLMNDWSARDIQKWEYVPLGPFTAKNLGTTIS 258
            |.|||||||: |.||:|||||.:.:|.:::||..|||||||||||||||||||||..|:.|||:|
Human   197 DMELEMAFFV-GPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVS 260

  Fly   259 PWVVPTAALKPFVLDNFPQEPEVLPYLRQNIPFNFDINLEVSLKPADQNE-ALISKSNFKHLYWT 322
            |||||..||.||.:.|..|:|..||||..:.|:.|||||.|:||....:: |.|.|||||::|||
Human   261 PWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFKYMYWT 325

  Fly   323 PLQQIAHHTVTGCNLRPGDLMASGTISGETPDSYGSLLELCWKGTKTLELPGGKTRKFLQDFDEV 387
            .|||:.||:|.|||||||||:|||||||..|:::||:|||.|||||.::|..|:|||||.|.|||
Human   326 MLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFLLDGDEV 390

  Fly   388 IIRGHCEKNGLRIGFGECVGQVLPA 412
            ||.|:|:.:|.|||||:|.|:||||
Human   391 IITGYCQGDGYRIGFGQCAGKVLPA 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Faa	NP_524830.2	PLN02856	1..414	CDD:215461	251/415 (60%)
FAH	NP_000128.1	fum_ac_acetase	2..416	CDD:162276	251/415 (60%)