Protein Alignment ida and APC5

DIOPT Version :10

• Sequence 1: NP_647837.2
• Gene: ida / 45574
• FlyBaseID: FBgn0041147
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_014892.3
• Gene: APC5 / 854423
• SGDID: S000005775
• Length: 685
• Species: Saccharomyces cerevisiae
• Alignment Length: 298
• Identity: 62/298 - (20%)
• Similarity: 105/298 - (35%)
• Gaps: 83/298 - (27%)

  Fly   233 EAVARIAQERNPLSKWAPKQAKFFINKQ-SELLENNERKALPPLELQKKVQE---IIHDL----- 288
            :|.::...|.|..:..:.:..:..:|:| ...|:|.|...:...|.....:|   ::.||
Yeast   227 DADSKTMNEENYGTLISIQHLQSIVNRQIVNWLDNTEFNLMGQEETSSTYEEQSGLVFDLLDTLS 291

  Fly   289 --PLTTTP--YFLGYMNQLRVRDYYNALSALHRALDRSPVRLMSQEKGYQYF---CVNLAVLHAT 346
              ..|..|  :.|.|:..::...|..||.:||...|     ..|......||   .::||..|::
Yeast   292 LNDATKFPLIFILKYLEAIKENSYQTALDSLHNYFD-----YKSTGNSQNYFHISLLSLATFHSS 351

  Fly   347 FGHRDEALAALRESIMLAQEHGDKRSLNL---------------ANTWYCLLRDELPLSAVQKSV 396
            |...|.|:.:..|:..:|:|:.|..:|||               ||.:|..:...:........|
Yeast   352 FNECDAAINSFEEATRIARENKDMETLNLIMIWIINFIEVHPEYANRFYITVEQIIKYLKNSSDV 416

  Fly   397 QDAN---------------------EVDGSLLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDN 440
            :|||                     ||..|||:      ..|:.|..|    |.:.|||.|
Yeast   417 EDANIFSNAYKFETLLSMVKESKTAEVSSSLLK------FMAITLQNV----PSQNFDLFQ---- 467

  Fly   441 LTNRNNFADHASEALALRSAVWSAYGRHELAALYSQVL 478
                        ..::.....|...|...::.:|.:.|
Yeast   468 ------------SLVSYEVKFWKELGYESISDVYEKFL 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ida	NP_647837.2	Apc5_N	48..191	CDD:293878
		TPR repeat	289..323	CDD:276806	10/35 (29%)
		COG3899	<294..505	CDD:443106	49/226 (22%)
		ANAPC5	295..386	CDD:432838	27/108 (25%)
		TPR repeat	333..366	CDD:276806	10/35 (29%)
APC5	NP_014892.3	TPR repeat	296..330	CDD:276806	10/38 (26%)
		ANAPC5	302..390	CDD:432838	24/92 (26%)
		TPR repeat	338..371	CDD:276806	9/32 (28%)