Protein Alignment ida and gfi-3

DIOPT Version :10

• Sequence 1: NP_647837.2
• Gene: ida / 45574
• FlyBaseID: FBgn0041147
• Length: 777
• Species: Drosophila melanogaster
• Sequence 2: NP_510409.1
• Gene: gfi-3 / 181544
• WormBaseID: WBGene00001583
• Length: 800
• Species: Caenorhabditis elegans
• Alignment Length: 649
• Identity: 128/649 - (19%)
• Similarity: 215/649 - (33%)
• Gaps: 175/649 - (26%)

  Fly   246 SKWAPK--------------QAKFFINKQSELLENNERKALPPLEL-------QKKVQEIIHDLP 289
            ||:.|:              :|:.::.|....::.|.|.|....|:       ||:..:::..
 Worm   205 SKYHPEFKGEYLPHFIDCSVRARDWVAKSIYFIQKNPRFAFQYNEMLHYTRIVQKRHPDVVEG-- 267

  Fly   290 LTTTPYFLGYMNQLRVRDYYNALSALHRALDRSPVRL--------------MSQEKGYQYFCVNL 340
                 :.|..:.|::::|..:|:.|:....:.|...|              :..:....|..:..
 Worm   268 -----FLLEAIVQVQLKDSSSAIKAMKSFFELSMFELNENMVHAAKTHRLAVPTQTPLMYAPILQ 327

  Fly   341 AVLHATFGHRDEALAALRESIMLAQEHGDKRSLNLANTWYCLLRDELPLSAVQKSVQDANEVDGS 405
            |.:...||....|...|.||:..||...|:....:||    :....:.:...:..::|.||....
 Worm   328 ARICRIFGDYQMARLLLHESLQQAQLRNDEICHQMAN----IEMHTVDILGCRALLEDNNEKTAK 388

  Fly   406 LLQNYTLALHFAVKLGTVAGYQPLRLFDLLQHSDN----LTNRNNF-----ADHASEALALRSAV 461
            .::|.......|:          |.:.||..|:.:    |::..:|     .|...:.|.|...:
 Worm   389 HIENERRVQRKAL----------LHIDDLHGHTRSGPCCLSSEEDFELVAEMDSYGKMLMLMKII 443

  Fly   462 WSAYGRHELAALYSQVLLTG---------RDRFGSGSAGLGSALASFALWLQLQGEPQLSKVLLH 517
              |.|.::|  :|.:|..||         .:| |...|..|:||.|         ...:...:.|
 Worm   444 --AEGNYKL--IYDRVAETGITCPVGNDLGER-GRKVAAYGAALIS---------SNMIHNGMYH 494

  Fly   518 HAK----------------QRFPRLPSAEGWMISQCHV-VIQAGIYQCRWHDALKACDQLYLIDP 565
            .||                ..|.....||.|.|...:: ..|||:  ..:..||:..:::....|
 Worm   495 QAKCAAENMLANNCRTDETDPFQAPFQAEPWAIGAVNLSYSQAGV--GNYDAALRTIEEMRQNYP 557

  Fly   566 SDSLFQRASIYVAKREFFNARRLLDK------------LAVQDNIPFLLRMRVQVLLGYCGMANG 618
            .:..:|.....|......|..|.|.|            ||....:.  .::|..:||...|  ..
 Worm   558 EELSWQSNRHVVICAAVINFERFLLKNDYKACASEVLNLAAHSELE--CKLRQALLLAAAG--KE 618

  Fly   619 RFSSET------------------TMLLLRVSEEMSEAQMDYELAL--------------VDLLL 651
            |.|.|.                  |..:...|:|..:|..::..||              |....
 Worm   619 RASVEVLEGLNVVDIRGRIRIHMQTGCIYTASQEFRKAAREFADALSLAENTTLKDIVPMVKRRQ 683

  Fly   652 ALQLLLLGMPQKAYQAIKRCMHDIHINGGLYERAKTDFVFVRC--LLAVNQNDAEKRKAQLLKSQ 714
            |..|:..|...:..:.:|.|...|...|...|:|.......||  ||.       |.....||..
 Worm   684 ATMLMCHGQYVECLKLLKECNEGIEQFGSFTEKACYYMTAARCHRLLG-------KDPRMWLKKS 741

  Fly   715 VILQRAAQ--SFKK--LSAHAKVLDVYVFLAQRFNEFGDRNLRNKYAGEFRRYFTDHPIPREYL 774
            ..|.|..|  :|.|  ||..|.:.||...:.       |.|..::...:|.:...|.|...|:|
 Worm   742 RALVRNGQWPAFTKLVLSEIAALHDVKGLMP-------DENRLSQICEQFGKLTADCPGRCEWL 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ida	NP_647837.2	Apc5_N	48..191	CDD:293878
		TPR repeat	289..323	CDD:276806	5/33 (15%)
		COG3899	<294..505	CDD:443106	48/242 (20%)
		ANAPC5	295..386	CDD:432838	20/104 (19%)
		TPR repeat	333..366	CDD:276806	9/32 (28%)
gfi-3	NP_510409.1	None