Protein Alignment Cyp6a17 and ERG11

DIOPT Version :9

• Sequence 1: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 534
• Identity: 122/534 - (22%)
• Similarity: 188/534 - (35%)
• Gaps: 123/534 - (23%)

  Fly     1 MLLLALIVVILSLLVFAARRRHG----YWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFK 61
            ::::..|..|:..|:::.|:...    ||    ||......::| :|.:       |.|.:...|
Yeast    34 IIIIPFIYNIVWQLLYSLRKDRPPLVFYW----IPWVGSAVVYG-MKPY-------EFFEECQKK 86

  Fly    62 YKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWR 126
            |        |..|.|.         ||.||:........:..||..::.|..:...::
Yeast    87 Y--------GDIFSFV---------LLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYA------- 127

  Fly   127 HLRHKLTPTFTSG------------------------KMKNMFPIVVKVGEEMDKVFR-SKTAAD 166
               |..||.|..|                        ..|:..|:   :.||:.|.|| ||....
Yeast   128 ---HLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPL---IAEEVYKYFRDSKNFRL 186

  Fly   167 RGQVLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGK--RAITE----HRYGNMLDIFL 225
            ..:....:|::.......|...:..|              :||  ||..:    :.|.::...|.
Yeast   187 NERTTGTIDVMVTQPEMTIFTASRSL--------------LGKEMRAKLDTDFAYLYSDLDKGFT 237

  Fly   226 ---FGFPKLSRRLRLKLNIQEAEDFYTKIVRETIDYRLRTKEKRNDFMD-SLIE-MYKNEQSGNS 285
               |.||      .|.|......|...|.:..|....::.:.|.||..| .||: :.||   ...
Yeast   238 PINFVFP------NLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKN---STY 293

  Fly   286 EDG--LTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYE 348
            :||  :|..|:........:.|..||:.|..:.|..||...|||.:|.||...|.....||.||:
Yeast   294 KDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYD 358

  Fly   349 GIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEP 413
            .::||..|.|.:.||||.:..|..|.|....|....:..|.|..|..|::.....|...:.:|..
Yeast   359 LLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNA 423

  Fly   414 EIFKPERFTDEE----------------IAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLI 462
            ..|...|:..:.                |:...|..:||||.|...|||..|...|..|.::..|
Yeast   424 HQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFI 488

  Fly   463 RGYKFSVSPETQIP 476
            |..|:.......:|
Yeast   489 RTLKWHYPEGKTVP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	114/495 (23%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	110/473 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960