DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a17 and CYP83A1

DIOPT Version :9

Sequence 1:	NP_001286433.1	Gene:	Cyp6a17 / 45556	FlyBaseID:	FBgn0015714	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_193113.1	Gene:	CYP83A1 / 827011	AraportID:	AT4G13770	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	529	Identity:	135/529 - (25%)
Similarity:	227/529 - (42%)	Gaps:	69/529 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNSDYPFAG 71
            :|.:.::|:|...::....:.:..|.....|:.||:... .|.:....|..:..||.    |...
plant     8 VVALAAVLLFFLYQKPKTKRYKLPPGPSPLPVIGNLLQL-QKLNPQRFFAGWAKKYG----PILS 67

  Fly    72 FFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTF 136
            :........|::..||.|.:|.....:|.:|        .|.....|...|::...|.| .||.:
plant    68 YRIGSRTMVVISSAELAKELLKTQDVNFADR--------PPHRGHEFISYGRRDMALNH-YTPYY 123

  Fly   137 TSGK---MKNMF-PIVV----KVGEE-----MDKVFRSKTAADRGQVLEVVDLVARYTADVIGNC 188
            ...:   |.::| |..|    .|.||     |||:   ..|||:.:|:::.:|:..:|..|:...
plant   124 REIRKMGMNHLFSPTRVATFKHVREEEARRMMDKI---NKAADKSEVVDISELMLTFTNSVVCRQ 185

  Fly   189 AFGLNCNSLYDPKAEFVSI--GKRAITEHRYGNML--DIFLF-GF-PKLSRRLRLKLNIQEAEDF 247
            |||...|...:....|:.|  |.:::    .|.:.  |.|.: || ..||..........|.:|.
plant   186 AFGKKYNEDGEEMKRFIKILYGTQSV----LGKIFFSDFFPYCGFLDDLSGLTAYMKECFERQDT 246

  Fly   248 Y-TKIVRETIDYRLRTKEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSST 311
            | .::|.||:|.: |.|.:....:|.|:.:|| ||...||  .|.:.:.|......|||.:|::.
plant   247 YIQEVVNETLDPK-RVKPETESMIDLLMGIYK-EQPFASE--FTVDNVKAVILDIVVAGTDTAAA 307

  Fly   312 TMGFALYELARNQDVQDKLREEIGNVFGKHNKEF-TYEGIKEMKYLEQVVMETLRKYPVLAHL-- 373
            .:.:.:..|.:...|..|.:.|:.....:....| |.:.:|.:.|...:|.||||..||:..|
plant   308 AVVWGMTYLMKYPQVLKKAQAEVREYMKEKGSTFVTEDDVKNLPYFRALVKETLRIEPVIPLLIP 372

  Fly   374 -TRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIY-PEPEIFKPERFTDEEIAAR-PSCTWL 435
             ..:.||..:    .|.|..||.|.:.|..:..|...: |.|:.|:||||.::|:..: ....::
plant   373 RACIQDTKIA----GYDIPAGTTVNVNAWAVSRDEKEWGPNPDEFRPERFLEKEVDFKGTDYEFI 433

  Fly   436 PFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGI------HL 494
            |||.|.|.|.|:|.|.....|..|.|:..:.|      ::|..:...:|.:....|:      ||
plant   434 PFGSGRRMCPGMRLGAAMLEVPYANLLLSFNF------KLPNGMKPDDINMDVMTGLAMHKSQHL 492

  Fly   495 KV--EKLAK 501
            |:  ||:.|
plant   493 KLVPEKVNK 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	123/467 (26%)
CYP83A1	NP_193113.1	PLN02966	1..502	CDD:178550	135/529 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910