DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a17 and LUT1

DIOPT Version :9

Sequence 1:	NP_001286433.1	Gene:	Cyp6a17 / 45556	FlyBaseID:	FBgn0015714	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	129/507 - (25%)
Similarity:	217/507 - (42%)	Gaps:	83/507 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GIP-----HDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNSDYPF----AGFFFFFTRTAVVTD 84
            |||     .|:|..|.|.....|            .:|:.|...|.    ||...|    .:|:|
plant    78 GIPIANAKLDDVADLLGGALFLP------------LYKWMNEYGPIYRLAAGPRNF----VIVSD 126

  Fly    85 MELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSI-EGQKWRHLRHKLTPT----FTSGKMKNM 144
            ..:.|.|| :::..:. :|: ..|:.:.|..:.|:| ||..|...|..:.|:    :.|..::.:
plant   127 PAIAKHVL-RNYPKYA-KGL-VAEVSEFLFGSGFAIAEGPLWTARRRAVVPSLHRRYLSVIVERV 188

  Fly   145 FPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNCNSLY--DPKAEFVSI 207
            |   .|..|.:  |.:.:..|:.|..:.:....::.|.||||...|..|.:||.  .|..|.|
plant   189 F---CKCAERL--VEKLQPYAEDGSAVNMEAKFSQMTLDVIGLSLFNYNFDSLTTDSPVIEAV-- 246

  Fly   208 GKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQEAEDFYTKIVRETIDYRL--------RTKE 264
                .|..:...:....|..:.|:....::.....:||...| ::|||::..:        |..|
plant   247 ----YTALKEAELRSTDLLPYWKIDALCKIVPRQVKAEKAVT-LIRETVEDLIAKCKEIVEREGE 306

  Fly   265 KRNDFMDSLIEMYKNEQSGN-------SEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELAR 322
            :.||      |.|.|:...:       |.:.::..:|........|||.||:.:.:.:.||.|::
plant   307 RIND------EEYVNDADPSILRFLLASREEVSSVQLRDDLLSMLVAGHETTGSVLTWTLYLLSK 365

  Fly   323 NQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDT-DFSPEDP 386
            |.....|.:||:..|....|..|  |.|||:||:.:.:.|::|.||....|.|.... |..|.:
plant   366 NSSALRKAQEEVDRVLEGRNPAF--EDIKELKYITRCINESMRLYPHPPVLIRRAQVPDILPGN- 427

  Fly   387 KYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCT-----WLPFGEGPRNCIG 446
             |.:..|..::|....||...:::.:.|.|.||||..:  .|.|:.|     ::||..|||.|:|
plant   428 -YKVNTGQDIMISVYNIHRSSEVWEKAEEFLPERFDID--GAIPNETNTDFKFIPFSGGPRKCVG 489

  Fly   447 LRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGIHLKVEK 498
            .:|.:|:..|.||..::.....:.|:..|.|   .....|...||:::||.:
plant   490 DQFALMEAIVALAVFLQRLNVELVPDQTISM---TTGATIHTTNGLYMKVSQ 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	118/473 (25%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	129/507 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810