DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cyp6a17 and CYP72A7

DIOPT Version :9

Sequence 1:NP_001286433.1 Gene:Cyp6a17 / 45556 FlyBaseID:FBgn0015714 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_188079.1 Gene:CYP72A7 / 820689 AraportID:AT3G14610 Length:512 Species:Arabidopsis thaliana


Alignment Length:556 Identity:143/556 - (25%)
Similarity:241/556 - (43%) Gaps:106/556 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 LLLALIVVILSLLVFAARRRHGYW----------QRRGIPHDEVHPLFGNIKDWPNKRHIAEIFR 56
            ::.||.|::..::::..|.....|          :|:|:......||.|:|     ||::     
plant     5 VVAALPVLVAVVVLWTWRIVKWVWIKPKMLESSLKRQGLTGTPYTPLVGDI-----KRNV----- 59

  Fly    57 DYYFKYKNSD-----------YPFA-------GFFFFF----TRTAVVTDMELLKRVLIKDFNHF 99
            |...:.::..           .|.|       |..||.    ..|.|:|:.|.:|.|..| .|.|
plant    60 DMMMEARSKPINVTDDITPRLLPLALKMLNSHGKTFFIWIGPLPTIVITNPEQIKEVFNK-VNDF 123

  Fly   100 ENRGVFYNEIDDP----LSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEM----D 156
            |....|      |    |:..|.|.:|.||...|..:.|.|...|:|||.|.......|:    :
plant   124 EKASTF------PLIRLLAGGLASYKGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWE 182

  Fly   157 KVFRSKTAADRGQVLEVVDL---VARYTADVIGNCAFGLNCN------SLYDPKAEFV--SIGKR 210
            |:|     .|:...|| ||:   :...|||||.:.|||.:..      .|....||.:  :..|.
plant   183 KLF-----TDKESPLE-VDVWPWLVNMTADVISHTAFGSSYKEGQRIFQLQGELAELIAQAFKKS 241

  Fly   211 AITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQEAEDFYTKIVRETIDYRLRTKE----KRNDFMD 271
            .|...|:          :|..|.| |:|...:|.:    .|:|..:..|.:.:|    ..:|.:.
plant   242 YIPGSRF----------YPTKSNR-RMKAIDREVD----VILRGIVSKREKAREAGEPANDDLLG 291

  Fly   272 SLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGN 336
            .|:|....|..||   |::..:::.:..:|:.||.||:|..:.:.:..|:.:||.|.:.|||:..
plant   292 ILLESNSEESQGN---GMSVEDVMKECKLFYFAGQETTSVLLVWTMVLLSHHQDWQARAREEVMQ 353

  Fly   337 VFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPAL 401
            |.|::||. ..|.:..:|.:..:..|.||.||.:|.|.|:.:.:....:  ..:..|..:.:|.:
plant   354 VLGENNKP-DMESLNNLKVMTMIFNEVLRLYPPVAQLKRVVNKEMKLGE--LTLPAGIQIYLPTI 415

  Fly   402 GIHYDPDIYPEPEI-FKPERFTDE-EIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRG 464
            .:..|.:::.:... ||||||.|. ..|.:...::.|||.|||.|||..|.|::..:.:|.:::.
plant   416 LVQRDTELWGDDAADFKPERFRDGLSKATKNQVSFFPFGWGPRICIGQNFAMLEAKMAMALILQK 480

  Fly   465 YKFSVSPE-TQIPMKIVVKNILISAENGIHLKVEKL 499
            :.|.:||. ...|..::...    .:.|.||.:.||
plant   481 FSFELSPSYVHAPQTVMTTR----PQFGAHLILHKL 512

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp6a17NP_001286433.1 p450 36..478 CDD:278495 131/489 (27%)
CYP72A7NP_188079.1 p450 21..512 CDD:299894 138/538 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm3438
orthoMCL 1 0.900 - - OOG6_100014
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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