Protein Alignment Cyp6a17 and Cyp4f18

DIOPT Version :9

• Sequence 1: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 421
• Identity: 114/421 - (27%)
• Similarity: 201/421 - (47%)
• Gaps: 47/421 - (11%)

  Fly   104 VFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSK--TAAD 166
            |||..:...|...|....|.||...|..|||.|..    |:....|||..:...:..:|  ..|.
Mouse   123 VFYRFLKPWLGDGLLMSTGDKWSRHRRMLTPAFHF----NILKPYVKVFNDSTNIMHAKWQRLAS 183

  Fly   167 RGQV-LEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITE------HRYGNML--- 221
            :|.. |.:.:.::..|.|.:..|.|..:.|....| :|:::    ||.|      .|:..:|
Mouse   184 KGSAYLNMFEHISLMTLDSLQKCVFSFDSNCQEKP-SEYIT----AILELSTLVARRHQRLLLHV 243

  Fly   222 DIFLFGFPKLSR-RLRLKLNIQEAEDFYTKIVRET---------ID-YRLRTKEKRNDFMDSLIE 275
            |:|.:    |:. .:|.:...:...||...::||.         :| .:.:.|.|..||:|.|:
Mouse   244 DLFYY----LTHDGMRFRKACRLVHDFTDAVIRERRRTLLDQGGVDVLKAKAKAKTLDFIDVLL- 303

  Fly   276 MYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVF-G 339
            :.|:|..    ..|:..::.|:|..|...|.:|:::.:.:.||.|||:.:.|::.|:|:..:. .
Mouse   304 LSKDEHG----KALSDEDIRAEADTFMFGGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRD 364

  Fly   340 KHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIH 404
            :..:|..::.:.::.:|...:.|:||.:|.:..::|....|....|.: .|.||.|..|...|.|
Mouse   365 REPEEIEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCTQDIVLPDGR-VIPKGVISRISIFGTH 428

  Fly   405 YDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSV 469
            ::|.::|:||::.|.||..:.:..|....::||..|||||||..|.|.:..|.||..:  .:|.|
Mouse   429 HNPAVWPDPEVYDPFRFDADNVKGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTL--LRFRV 491

  Fly   470 SPETQIPMKIVVKNILISAENGIHLKVEKLA 500
            .|:.:.|.:  ...:::.||.|:.||||.|:
Mouse   492 LPDDKEPRR--KPELILRAEGGLWLKVEPLS 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	106/397 (27%)
Cyp4f18	NP_077764.2	p450	52..516	CDD:365848	110/415 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2076
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930