Protein Alignment Cyp6a17 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 568
• Identity: 119/568 - (20%)
• Similarity: 203/568 - (35%)
• Gaps: 119/568 - (20%)

  Fly     2 LLLALIVVILSLLVFAARRRHGYWQ-RRGIPHDEV--HPLFGNIKDWPNKRHIAEIFRDYYFKYK 63
            ||.....|:.::|:.|..|.  .|: |..|..|..  .||......||   .:.|.|.
Zfish    12 LLSVADAVLPTVLLLAVSRL--LWEFRWSITRDRTCKLPLPQGSMGWP---LVGETFH------- 64

  Fly    64 NSDYPFAGFFFFFTRT---AVVTDMELLKRVLIKDFNHFENRGVFYNE-----IDDPLSA----- 115
               :.|.|..|..:|.   ..|....||.:.||:.......|.:...|     ...|.|.
Zfish    65 ---WLFQGSSFHISRREKHGKVFKTHLLGKPLIRVTGAENIRKILLGEHTVVCTQWPQSTRIILG 126

  Fly   116 --TLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTA---ADRGQVLEVVD 175
              ||.:..|...:..|..|...|:.|.::...       ..:..|.:|:.|   .:.|.| ||..
Zfish   127 PNTLVNSVGDLHKRKRKVLAKVFSRGALEAYL-------TRLQDVVKSEIAKWCTETGSV-EVYT 183

  Fly   176 LVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLN 240
            .....|..:......||:   |.:.:..::|.....:..:.:...:|..:.|   |.:.:|.:..
Zfish   184 AAKSLTFRIAVRVLLGLH---LEEQQITYLSKTFEQLMNNLFSLPIDTPVSG---LRKGIRAREI 242

  Fly   241 IQEAEDFYTKIVRETIDYRLRTKEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAG 305
            :..|.:   ||:.|.:     .|::.:|:.|:...|..:.:..:.|  ||..||...|.....|.
Zfish   243 LHSAME---KIIEEKL-----KKQQASDYCDAFDYMLSSARENDYE--LTMQELKETAVELIFAA 297

  Fly   306 FETSSTTMGFALYELARNQDVQDKLREEI------------------GNVFGKHNK--------- 343
            ..|:::.....:.:|.|:.||.::.|.|:                  ||...:..:
Zfish   298 HSTTASASTSLIMQLLRHPDVSERARAELESEGLITDGHGHCRSRCNGNAISEEGEAAEKSTSDR 362

  Fly   344 -----EFTY---------------------EGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFS 382
                 :.||                     |.:.::.||:.||.|.||..|.::...|.....|
Zfish   363 RSAINKATYFEAGDKEEGRRSRTHVPYLSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTVLQTF- 426

  Fly   383 PEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERF-TDEEIAARPSCTWLPFGEGPRNCIG 446
             |...|.|.||..|:......|...:.|..||:|.|:|| ...|.:.....:::|||.|.|.|||
Zfish   427 -ELNGYQIPKGWSVMYSIRDTHETAEAYQNPELFDPDRFCVGREESKSERFSYVPFGGGVRRCIG 490

  Fly   447 LRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGIHL 494
            ....::........|:.....:::.:|...|:.|.   ::...||:|:
Zfish   491 RELALIVLKTLAVELLATADCTLATQTYPRMQTVP---IVHPVNGLHV 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	102/498 (20%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	105/516 (20%)