Protein Alignment Cyp6a17 and Cyp3a44

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 506
• Identity: 173/506 - (34%)
• Similarity: 278/506 - (54%)
• Gaps: 36/506 - (7%)

  Fly     4 LALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNSDYP 68
            |.|:.:||.||.....|.||.::::|||..:..|..|.:.::  ...|.:...:.|.||..:
Mouse    12 LVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNY--YTGIWKFDMECYEKYGKT--- 71

  Fly    69 FAGFFFFFTRTAVVTDMELLKRVLIKD-FNHFENRGVFYNEIDDP---LSATLFSIEGQKWRHLR 129
             .|.|...|...|:||.|.:|.||:|| .:.|.||..|     .|   :|..:...:.::|:..|
Mouse    72 -WGLFDGQTPLLVITDPETIKNVLVKDCLSVFTNRREF-----GPVGIMSKAISISKDEEWKRYR 130

  Fly   130 HKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNC 194
            ..|:||||||::|.|||::.:.|:.:.|..|.:  |::|..:.:.|::..|:.|||.:.:||:|.
Mouse   131 ALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQE--AEKGMPVAMKDVLGAYSMDVITSTSFGVNV 193

  Fly   195 NSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFG---FPKLSRRLRLKLNI----QEAEDFYTKIV 252
            :||.:|:..||...|:.:..    :..|..||.   ||.|:....: |||    .::.:|:.|.|
Mouse   194 DSLNNPEDPFVEEAKKFLRV----DFFDPLLFSVVLFPLLTPVYEM-LNICMFPNDSIEFFKKFV 253

  Fly   253 RETIDYRLRTKEK-RNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFA 316
            ....:.||.:.:| |.||:..::..:.|.:..:|....:..|:..|:.||..||:||:|:|:.|.
Mouse   254 DRMQESRLDSNQKHRVDFLQLMMNSHNNSKDKDSHKAFSNMEITVQSIIFISAGYETTSSTLSFT 318

  Fly   317 LYELARNQDVQDKLREEIGNVFGKHNKEF-TYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTD 380
            ||.||.:.|:|.||:.||....  .||.. |.:.:.||:||:.|:.||||.||::..|.|:...|
Mouse   319 LYCLATHPDIQKKLQAEIDKAL--PNKATPTCDTVMEMEYLDMVLNETLRLYPIVTRLERVCKKD 381

  Fly   381 FSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCI 445
            .  |....:|.||::|:||:..:|:||..:|:||.|:||||:.|...:.....:||||.||||||
Mouse   382 V--ELNGVYIPKGSMVMIPSYALHHDPQHWPDPEEFQPERFSKENKGSIDPYVYLPFGIGPRNCI 444

  Fly   446 GLRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGIHLKV 496
            |:||.:|...:.:..:::.:.|....|||||:|:..:.|| ..|..|.|||
Mouse   445 GMRFALMNMKLAVTKVLQNFSFQPCQETQIPLKLSRQGIL-QPEKPIVLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	151/439 (34%)
Cyp3a44	NP_796354.1	CYP3A	67..493	CDD:410743	154/446 (35%)