Protein Alignment Cyp6a17 and Cyp4a12a

DIOPT Version :9

• Sequence 1: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 544
• Identity: 134/544 - (24%)
• Similarity: 239/544 - (43%)
• Gaps: 108/544 - (19%)

  Fly     7 IVVILSLLVFAARRRHGYWQRRGI-------PHDEVHPLFGN--IKDWPNKRHIAEIFRDYYFKY 62
            :..:||||:...:....|..|:.:       |....|.|||:  :||        :..:|...:.
Mouse    21 VASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGHKILKD--------QDLQDILTRI 77

  Fly    63 KNSDYPFA-GFFFFFTRTAV-VTDMELLKRVLIKDFNHFENRGVFYNEIDDP------------L 113
            ||  :|.| ..:.:.::..: |.|.:.:|.:|.:               .||            :
Mouse    78 KN--FPSACPQWLWGSKVRIQVYDPDYMKLILGR---------------SDPKANGSYRFLAPWI 125

  Fly   114 SATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQ--VLEVVDL 176
            ...|..::||.|...|..|||.|....:|....|:.    :..:|...|.....||  .||:...
Mouse   126 GRGLLMLDGQTWFQHRRMLTPAFHYDILKPYTEIMA----DSVRVMLDKWEQIVGQDSTLEIFRH 186

  Fly   177 VARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIF-----LFGFP------- 229
            :...|.|.|..|||....:...|.|.:........:.:..:..:.:||     ::...
Mouse   187 ITLMTLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNDLVFSRVRNIFHQNDIIYRVSSNGCKAN 251

  Fly   230 ---KL----------SRRLRLKLNIQEAEDFYTKIVRETIDYRLRTKEKRNDFMDSLIEMYKNEQ 281
               ||          |||::|    |:.|:.          .:|: |::|.||:|.|  ::...:
Mouse   252 SACKLAHDHTDQVIKSRRIQL----QDEEEL----------EKLK-KKRRLDFLDIL--LFARME 299

  Fly   282 SGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFT 346
            :|.|   |:..:|.|:...|...|.:|:::.:.:..|.||.|.:.|.:.|:||.::.| .....|
Mouse   300 NGKS---LSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLG-DGTSIT 360

  Fly   347 YEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYP 411
            :..:.:|.|....:.|.||.||.:..::|...:..:..|.: .:.||..|::...|:|::|.::|
Mouse   361 WNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGR-SLPKGIHVMLSFYGLHHNPTVWP 424

  Fly   412 EPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPE-TQI 475
            .||:|.|.||...  ::|.|.::|||..|.|||||.:|.|.:..|.:|..:  .:|.:.|: |::
Mouse   425 NPEVFDPSRFAPG--SSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTL--LRFELLPDPTRV 485

  Fly   476 PMKIVVKNILISAENGIHLKVEKL 499
            |  |.:..|::.::|||||.::||
Mouse   486 P--IPIPRIVLKSKNGIHLHLKKL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	118/485 (24%)
Cyp4a12a	NP_803125.2	p450	52..502	CDD:278495	124/506 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900