Protein Alignment Cyp6a17 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 130/540 - (24%)
• Similarity: 235/540 - (43%)
• Gaps: 96/540 - (17%)

  Fly     6 LIVVILSLLVFAARRRHGYWQR-RGIPH-DEVHPLFGN---IKDWPNKRHIAEIFRDYYFKYKN- 64
            :::.||.:||..||:    ||: |.||. ...:||.|:   :|  ||.....:....|..::::
  Rat    29 VLLNILQMLVSYARK----WQQMRPIPSVARAYPLVGHALFMK--PNNTEFFQQIIQYTEEFRHL 87

  Fly    65 -------SDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEG 122
                   ...|....:.......::|..:.:            ::...|..:...|...|.:..|
  Rat    88 PIIKLWIGPVPLVALYKAENVEVILTSSKQI------------DKSFMYKFLQPWLGLGLLTSTG 140

  Fly   123 QKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDL---VARYTADV 184
            .|||..|..|||:|....:::...::    .|...:..:|......|  |..:.   :.....|:
  Rat   141 SKWRARRKMLTPSFHFTILEDFLDVM----NEQANILVNKLEKHVNQ--EAFNCFFPITLCALDI 199

  Fly   185 IGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRL------------ 237
            |...|.|.|..:..:..:|:|.      |.:|..:|          :.||:::
  Rat   200 ICETAMGKNIGAQSNGDSEYVR------TVYRMSDM----------IYRRMKMPWFWFDLWYLMF 248

  Fly   238 ------KLNIQEAEDFYTKIVRETIDYR-------------LRTKEKRNDFMDSLIEMYKNEQSG 283
                  |..::....|...::.|.::.|             |.:|.||..|:|.|:.:  .::.|
  Rat   249 KEGRDHKKGLKSLHTFTNNVIAERVNARKAEQDCIGAGRGPLPSKTKRKAFLDLLLSV--TDEEG 311

  Fly   284 NSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYE 348
            |.   |:..::..:...|...|.:|::..:.::||.|..|.:||.|:.:|:.:|||:.::..|.|
  Rat   312 NK---LSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSHRPVTLE 373

  Fly   349 GIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEP 413
            .:|::|||:.|:.||||.:|.:....|....|.  |...|.|:|||..||....:|.||..:|:|
  Rat   374 DLKKLKYLDCVIKETLRVFPSVPLFARSLSEDC--EVAGYKISKGTEAVIIPYALHRDPRYFPDP 436

  Fly   414 EIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIPMK 478
            |.|:||||..|....|....::||..|||||||.:|.:|:....||.::|  :|.:....:....
  Rat   437 EEFQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILR--EFWIESNQKREEL 499

  Fly   479 IVVKNILISAENGIHLKVEK 498
            .:..::::...|||.:|:::
  Rat   500 GLAGDLILRPNNGIWIKLKR 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	110/460 (24%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	112/481 (23%)