Protein Alignment Cyp6a17 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 145/532 - (27%)
• Similarity: 259/532 - (48%)
• Gaps: 52/532 - (9%)

  Fly     1 MLLLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNS 65
            ::.:.|.||:|:||.:.:.......::.||.|.|..|..||:      ....:.|.:.:.:.:..
  Rat    15 VVTVTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPSPFVGNL------MFFRQGFWESHLELRER 73

  Fly    66 DYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSA-TLFSIEGQKWRHLR 129
            ..|..|::.......|::|.:::|.||:::|::|.||  ..:.::..|.| ::..:..::|..:|
  Rat    74 YGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNR--MASGLEPKLIADSVLMLRDRRWEEVR 136

  Fly   130 HKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNC 194
            ..|...|:..|:..|.|::.:..|.:  :...|.:|..|...::......:|.:|:.:.|||:..
  Rat   137 GALMSAFSPEKLNEMTPLISQACELL--LSHLKHSAASGDAFDIQRCYCCFTTNVVASVAFGIEV 199

  Fly   195 NSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPK----LSRRLRLKLNIQEAEDFYTKIVRET 255
            ||...|:..||...:|.........:|.:.| .||.    |:|.|..| |..|...|:..::|..
  Rat   200 NSQDAPEDPFVQHCQRVFAFSTPRPLLALIL-SFPSIMVPLARILPNK-NRDELNGFFNTLIRNV 262

  Fly   256 IDYRLR--TKEKRNDFMDSLIEMYKNEQSGNSE----------------------------DGLT 290
            |..|.:  .:|:|.||:..:::..::..|...|                            ..||
  Rat   263 IALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSAECMGDPPQRCHPTSTAKPLT 327

  Fly   291 FNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKE-MK 354
            .:|:..|||:|.:||.|.::.|:.|..|.||.:.:.|::|.:|:.....||... .|..::| :.
  Rat   328 VDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHPAP-EYCNLQEGLP 391

  Fly   355 YLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPE 419
            ||:.||.||||.||.....||....|.  |.....|..|:::.|....:|:||:.:|.||.|.||
  Rat   392 YLDMVVAETLRMYPPAFRFTREAAQDC--EVLGQHIPAGSVLEIAVGALHHDPEHWPNPETFDPE 454

  Fly   420 RFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNI 484
            |||.|....:...|:||||.|||:|:|:|.|::...:.|..::..::|...||||:|:::..|:.
  Rat   455 RFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPETQVPLQLESKSA 519

  Fly   485 LISAENGIHLKV 496
            | ..:||:::|:
  Rat   520 L-CPKNGVYVKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	130/462 (28%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	130/462 (28%)