Protein Alignment Cyp6a17 and cyp-13A4

DIOPT Version :9

• Sequence 1: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 151/544 - (27%)
• Similarity: 257/544 - (47%)
• Gaps: 103/544 - (18%)

  Fly     5 ALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDY----------Y 59
            ||.:..|:..::.    ..:|.|:|:......|.||.|..          |.||          :
 Worm    10 ALFIGFLTYYIWI----WSFWIRKGVKGPRGFPFFGVILK----------FHDYENPGLLKLGEW 60

  Fly    60 FKYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEID-DP---LSATLFSI 120
            .|...|.|   |......:|.||::.|.:..|.:|.|::|..|..  |.|. ||   ..|.|...
 Worm    61 TKKYGSIY---GITEGVEKTLVVSNPEFVHEVFVKQFDNFYGRKT--NPIQGDPNKNKRAHLVLA 120

  Fly   121 EGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRS-KTAADRGQVLEVVDLVARYTADV 184
            :|.:|:.||...:|||::   |::..|:..|.|.:.::.|. ..|:.:|:.::::|....:|.|:
 Worm   121 QGHRWKRLRTLASPTFSN---KSLRKIMSTVEETVVELMRHLDEASAKGKAVDLLDYYQEFTLDI 182

  Fly   185 IGNCAFGLNCNSLY-DP-------------KAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRL 235
            ||..|.|...:.:: :|             |..|:..|...|.    |.::......|||.|...
 Worm   183 IGRIAMGQTESLMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIA----GTLMRQLFMKFPKFSPAF 243

  Fly   236 RLKLNIQEAEDFYTKIVRETIDYRLRTKE-------KRNDFMDSLIEMYKN-----EQS----GN 284
            .: :|..|      |.:.:.::.|...|:       :..||:|..::...|     |:|    ..
 Worm   244 GI-MNTME------KALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEESTLGFAK 301

  Fly   285 SE-----DGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKE 344
            ||     ..|||:|::.|.|:|.:||::|::.::.::.|.||.:.::|.||:||:....  .:.|
 Worm   302 SEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDREC--PDPE 364

  Fly   345 FTYEGIKEMKYLEQVVMETLRKYPV--LAHLTR-MTDTDFSPEDPKYFIAKGTIVVIPALGIHYD 406
            .|::.|.::||:|.||.|.||.||:  |.|..: |..|:....:    |.:||.|.:....:|||
 Worm   365 VTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKKTNVLGVE----IDEGTNVQVDTWTLHYD 425

  Fly   407 PDIY-PEPEIFKPERFT--DEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFS 468
            |.:: .:...|||||:.  ||...|:..  :||||.|||.|||:|..||:..:.|.::::.|.|.
 Worm   426 PKVWGDDASEFKPERWETGDELFYAKGG--YLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFD 488

  Fly   469 VSPETQIPMKIV------VKNILI 486
            .|.||:||:|:|      .:|:::
 Worm   489 TSTETEIPLKLVGSATIAPRNVML 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	142/497 (29%)
cyp-13A4	NP_496111.1	p450	33..514	CDD:278495	145/517 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I2666
Isobase	1	0.950	-	0	Normalized mean entropy	S3417
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2076
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.760