DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a17 and cyp-25A6

DIOPT Version :9

Sequence 1:	NP_001286433.1	Gene:	Cyp6a17 / 45556	FlyBaseID:	FBgn0015714	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001360017.1	Gene:	cyp-25A6 / 187059	WormBaseID:	WBGene00019438	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	62/244 - (25%)
Similarity:	104/244 - (42%)	Gaps:	48/244 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLLALIVVILSLLVFAARRRHGYWQRR---GIPHDEVHPLFGNIK---------------DWPN 47
            ::|.:::|.::|.:::....|...::.|   |:...|.|.|.||:|               ||.|
Worm     4 LILTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSYDWYN 68

  Fly    48 KRH--IAEIFRDYYFKYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRG----VFY 106
            |.|  ..|.|               |.:|.......:|:.|.:|.|.||:|::|.:|.    :..
Worm    69 KLHKQFGETF---------------GIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIED 118

  Fly   107 NEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVL 171
            |::.:.|....:.   ..|:|.|..:.|.|::||||.|...:....:...::.:.|  |..||..
Worm   119 NKLKESLLQNTYE---SGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEK--ASSGQKW 178

  Fly   172 EVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAIT----EHR 216
            ::.|.....|.||||.|||.::.|...|....|....::.||    .||
Worm   179 DIYDDFQGLTLDVIGKCAFAIDSNCQRDRNDIFYVNARKFITNIDIRHR 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	55/206 (27%)
cyp-25A6	NP_001360017.1	p450	37..>215	CDD:386267	52/197 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720