Protein Alignment Cyp6a17 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 150/495 - (30%)
• Similarity: 229/495 - (46%)
• Gaps: 81/495 - (16%)

  Fly     1 MLLLALIVVILSLLVF------AARRRHGYWQRRGIPHDEVHPLFGNIKD--------------- 44
            |.||.|..:::|:..|      |.|.|....::.|:...|.|...||:|.
 Worm     1 MALLILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDANR 65

  Fly    45 WPNKRH--IAEIFRDYYFKYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGV--F 105
            |.|:.|  ..|.|..||....|               .|:::.:.:|.|.||:|::|.:|.|  .
 Worm    66 WFNELHEQYGETFGIYYGSQMN---------------IVISNEKDIKEVFIKNFSNFSDRSVPSI 115

  Fly   106 YNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIV-VKVGEEMDKVFRSKTAADRGQ 169
            | |.:...::.|.:.....|:|.|..:.|.|::||||.|...: .||...:| :.|.|  |..||
 Worm   116 Y-EANQLTASLLMNSYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLD-ILREK--ASSGQ 176

  Fly   170 VLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRR 234
            ..::.|.....|.||||.|||.::.|...|....|.      :...:|.:.:||      :.|:.
 Worm   177 KWDIYDDFQGLTLDVIGKCAFAIDSNCQRDRNDVFY------VNAKKYISNIDI------RHSKI 229

  Fly   235 LRLKLNIQEAEDF------YTKIVRETID--------YRLRTKEKRNDFMDSLIEMYKNEQSGNS 285
            :...:.:.|...|      ||.:....|.        |..|...:.:|.:| |:::..|.:...|
 Worm   230 IAASVLLPELSTFWKALYKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVD-LLKLLLNREDDKS 293

  Fly   286 EDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGI 350
            :. :|..|::...|.|.:||:||:||.|.:..|.|::..:||.||.|||  :..|.|...||:.|
 Worm   294 KP-MTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEI--MEAKENGGLTYDSI 355

  Fly   351 KEMKYLEQVVMETLRKYPVLAH-LTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPE 414
            ..||||:.|..||||.||.:.| :.|:...|.:...  .|..||.|||.....:|.:|:.:..||
 Worm   356 HNMKYLDCVYKETLRFYPPVIHFIRRLCREDITIRG--QFYPKGAIVVCLPHTVHRNPENWDSPE 418

  Fly   415 IFKPERFTD-EEIAARPSCTWLPFGEGPRNCIGLRFGMMQ 453
            .|.||||.: ||.::  |..|:|||.|||.|:|:||..|:
 Worm   419 EFHPERFENWEEKSS--SLKWIPFGVGPRYCVGMRFAEME 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	127/407 (31%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	132/423 (31%)