Protein Alignment Cyp6a17 and cyp-43A1

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_508961.3
• Gene: cyp-43A1 / 180838
• WormBaseID: WBGene00017108
• Length: 526
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 130/545 - (23%)
• Similarity: 233/545 - (42%)
• Gaps: 125/545 - (22%)

  Fly     1 MLLLALIVVILSLLVFAARRRHGYWQRR-GI-PHDEVHPLFGNIKDW-------PNKRHIAEIFR 56
            |:||.|:.|.:...||....:..|...: |: |..::..:.|.:  |       .|...:..:..
 Worm     1 MILLILLPVAIFTYVFLRNFKLYYTLHKCGLNPRFDIFGIKGLL--WLDSSAAHENFTRMCSMIG 63

  Fly    57 DYYFKYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEI--DDPLSAT--- 116
            |..|.......|          ..:.::::|:..:..:.|:.|.:|   ..||  |||:::.
 Worm    64 DQTFSVLRGATP----------VVITSNVDLIHAISTEHFDCFHSR---IPEILSDDPITSDNIH 115

  Fly   117 LFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIV-VKVGEEMDKVFRSKTAADRGQVLEV---VDLV 177
            :|:.:|::|:.||...:...::.|:|.:||.: ..|.|.||.|    .:...||.:.:   ..|.
 Worm   116 MFAAKGERWKRLRTLTSYGLSTVKLKLLFPTMDTCVSEFMDHV----NSLSDGQSVVINHSHSLF 176

  Fly   178 ARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIF--LFG-FPKLSRRLRLKL 239
            ..:|:.|:..||:|      :..|            .||..|.|.:|  .|| |.:|.:....|:
 Worm   177 QNHTSYVLARCAYG------HKEK------------NHRVNNFLGVFSKAFGNFAELQKSTAEKI 223

  Fly   240 NIQEAEDFYTKIV--RETIDYRLR--TKEKRNDFMDSLIEMYKNEQSGNS--------------- 285
            .....|   ||::  ...:.:.|:  |::|   |:|.|:.:..|.||..:
 Worm   224 AYIFPE---TKLIFKNSFVGHFLKSATQQK---FLDYLLHLISNFQSRKNVDNNNGICCTENDHY 282

  Fly   286 ------------------------------EDGLTFNELLAQAFIFFVAGFETSSTTMGFALYEL 320
                                          |..:::.|:.||.....||||:|:|.|:......|
 Worm   283 SLLGFFFEHHNEKKLIEKAEGQIDMKKVKVEKSISYEEITAQCKFISVAGFDTTSNTLTLLFNFL 347

  Fly   321 ARNQDVQDKLRE-EIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHL-TRMTDTDFSP 383
            |.|.|||||:.| ||.|    ..::.::|.:..::.|:..:.||||.:|..:.| ||:....|
 Worm   348 ANNPDVQDKIYEAEIKN----QPEQISFETVSSLRLLQNCIFETLRLFPHASPLQTRICTEPF-- 406

  Fly   384 EDPKYFIAKGTIVVIPALGIHYDPDIY-PEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGL 447
            :..||...:...:|:...|.|:|.:|: .:.:.|:|.||  |.:..:....::|||.|||.|:|:
 Worm   407 KIGKYQFLENVQIVVNPWGPHHDREIWGNDVDCFRPSRF--ENLTEQQRKAFMPFGVGPRQCVGM 469

  Fly   448 RFGMMQTCVGLAYLIRGYK-FSVSP 471
            ||.:::.......:::.|. |:.||
 Worm   470 RFALLEMKTTAFRMLQKYSVFTNSP 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	115/471 (24%)
cyp-43A1	NP_508961.3	cytochrome_P450	64..514	CDD:477761	117/480 (24%)