Protein Alignment Cyp6a17 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_569092.2
• Gene: Cyp26a1 / 154985
• RGDID: 620161
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 487
• Identity: 103/487 - (21%)
• Similarity: 180/487 - (36%)
• Gaps: 83/487 - (17%)

  Fly     1 MLLLALIVVILSLLVFAARRRHGYWQRRGI------------PHDEVHPLFGNIKDW--PNKRHI 51
            :|..||...:|.||:|.|..:  .|....:            |.....|.||.....  ..::.:
  Rat     6 LLASALCTFVLPLLLFLAALK--LWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFL 68

  Fly    52 AEIFRDYYFKYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLS-- 114
            ....|.|.|.||.        ..|...|..|...:.::|:|:.     |:|.|   .:..|.|
  Rat    69 QMKRRKYGFIYKT--------HLFGRPTVRVMGADNVRRILLG-----EHRLV---SVHWPASVR 117

  Fly   115 -----ATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRS-KTAADRGQVL-- 171
                 ..|.::.....:..:..:...|....::...|:   :.||:...... .:..:||.::
  Rat   118 TILGAGCLSNLHDSSHKQRKKVIMQAFNREALQCYVPV---IAEEVSGCLEQWLSCGERGLLVYP 179

  Fly   172 EVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLR 236
            ||..|:.|....::..|..|.....  :.:.:.|...:. :|.:.:...:|:   .|..|.|.::
  Rat   180 EVKRLMFRIAMRILLGCEPGPAGGG--EDEQQLVEAFEE-MTRNLFSLPIDV---PFSGLYRGVK 238

  Fly   237 LKLNIQEAEDFYTKIVRETIDYRLRTKEKR----------NDFMDSLIEMYKNEQSGNSEDGLTF 291
            .:           .::...|:..:|.|.:|          .|.:..||     |.|....:.|..
  Rat   239 AR-----------NLIHARIEENIRAKIRRLQAAEPDAGCKDALQLLI-----EHSWERGERLDM 287

  Fly   292 NELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEI---GNVFGKHNKE-FTYEGIKE 352
            ..|...:......|.||:::.....:..|.....|..|:||||   |.:...|::: ...|.:::
  Rat   288 QALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSHHEDKLDMETLEQ 352

  Fly   353 MKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFK 417
            :||:..|:.||||..|.:....|:....|  |...|.|.||..|:......|...|.:...|.|.
  Rat   353 LKYIGCVIKETLRLNPPVPGGFRVALKTF--ELNGYQIPKGWNVIYSICDTHDVADSFTNKEEFN 415

  Fly   418 PERFTDEEIAARPSCTWLPFGEGPRNCIGLRF 449
            |:|||..........:::|||.|.|:|:|..|
  Rat   416 PDRFTSLHPEDTSRFSFIPFGGGLRSCVGKEF 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	85/408 (21%)
Cyp26a1	NP_569092.2	cytochrome_P450	55..490	CDD:477761	91/436 (21%)