Protein Alignment Cyp6a17 and Cyp4a14

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 552
• Identity: 134/552 - (24%)
• Similarity: 228/552 - (41%)
• Gaps: 124/552 - (22%)

  Fly     3 LLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHP---LFG-NIKD--------WPNK------- 48
            ||:|.:|:...:.|..||:   |..:.:.|....|   |:| ::||        |..|
Mouse    24 LLSLFLVLFKAVQFYLRRQ---WLLKTLQHFPCMPSHWLWGHHLKDKELQQILIWVEKFPSACLQ 85

  Fly    49 ----RHIAEIFRD-YYFK--YKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFY 106
                .:|..:..| .|.|  ...||...:|.:.||.
Mouse    86 CLSGSNIRVLLYDPDYVKVVLGRSDPKASGIYQFFA----------------------------- 121

  Fly   107 NEIDDP-LSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQ- 169
                 | :...|..:.|:||...|..|||.|....:|.    .||:..:...:...|.....||
Mouse   122 -----PWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKP----YVKIMADSVNIMLDKWEKLDGQD 177

  Fly   170 -VLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSR 233
             .||:...|:..|.|.:..|||....:...|..::..:   :|:.:.   |.|..|
Mouse   178 HPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYT---KAVEDL---NNLTFF--------- 227

  Fly   234 RLR---LKLNI------------------QEAEDFYTKIVRETI----DYRLRTKEKRNDFMDSL 273
            |||   .|.||                  .|..|...|:.:..:    :.:...|::..||:|.|
Mouse   228 RLRNAFYKYNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQNEEELQKARKKRHLDFLDIL 292

  Fly   274 IEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVF 338
              ::...:..||   |:..:|.|:...|...|.:|:::.:.:..|.||.:.:.|.:.|||:.::.
Mouse   293 --LFARMEDRNS---LSDEDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQSIL 352

  Fly   339 GKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGI 403
            | .....|::.:.:|.|....:.|.||.||.:..::|...:..:..|.: .|.||....|...|:
Mouse   353 G-DGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTFPDGR-SIPKGITATISIYGL 415

  Fly   404 HYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFS 468
            |::|..:|.|::|.|.||..:  ::..|..:|||..|.|||||.:|.|.:..|.:|..:  .:|.
Mouse   416 HHNPRFWPNPKVFDPSRFAPD--SSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTL--LRFE 476

  Fly   469 VSPE-TQIPMKIVVKNILISAENGIHLKVEKL 499
            :.|: |:||:.|.  .:::.::|||||.::||
Mouse   477 LLPDPTRIPVPIA--RLVLKSKNGIHLCLKKL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	108/455 (24%)
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	117/498 (23%)