Protein Alignment Cyp6a17 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 542
• Identity: 137/542 - (25%)
• Similarity: 240/542 - (44%)
• Gaps: 96/542 - (17%)

  Fly     2 LLLALIVVILSLLVFAAR-RRHGYWQRRG---IPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKY 62
            |.:|.::.:|.|||.|.: ..|..|..:.   .|....|..||:.| :...:.:.||....
Mouse    19 LQVASVLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFFGHEK-FKGDQELQEIVSCI---- 78

  Fly    63 KNSDYPFAGFFFFFTRTAVVT--DMELLKRVLIKDFNHFENRGVFYNEIDDP------------L 113
              .::|.|...:|:...|.:|  |.:.:|.:|.:               .||            :
Mouse    79 --ENFPSAFPRWFWGSKAYLTVYDPDYMKVILGR---------------SDPKANGAYRLLAPWI 126

  Fly   114 SATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEE----MDKVFRSKTAADRGQVLEVV 174
            ...|..:.||.|...|..|||.|....:|   |.|..:.:.    :||..|   .||:...:|:.
Mouse   127 GYGLLLLNGQPWFQHRRMLTPAFHYDILK---PYVKNMADSIRLMLDKWER---LADQDSSIEIF 185

  Fly   175 DLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIF------LF----GFP 229
            ..::..|.|.:..|||....:...|        |.........|::.::|      :|    ...
Mouse   186 QHISLMTLDTVMKCAFSHKGSVQVD--------GNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIY 242

  Fly   230 KLSRRLRL-KLNIQEAEDFYTKIVRETIDYRLR--------TKEKRNDFMDSLIEMYKNEQSGNS 285
            |||...|| |...|.|.|....:::...| :|:        .|::|.||:|.|  ::...::|
Mouse   243 KLSSNGRLAKQACQLAHDHTDGVIKLRKD-QLQDEGELEKIKKKRRLDFLDIL--LFARMENG-- 302

  Fly   286 EDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGI 350
             |.::..:|.|:...|...|.:|:::.:.:..|.||.:.|.|.:.|||:.::.| .....|::.:
Mouse   303 -DSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLG-DGSSITWDHL 365

  Fly   351 KEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEI 415
            .::.|....:.|.||.||.:..:.|...|..:..|.: .:.||..|.:...|:|::|.::|.||:
Mouse   366 DQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGR-SLPKGVQVTLSIYGLHHNPKVWPNPEV 429

  Fly   416 FKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGM--MQTCVGLAYLIRGYKFSVSPE-TQIPM 477
            |.|.||..:  :.|.|.::|||..|.|||||.:|.|  ::..|.|..|    :|.:.|: |::||
Mouse   430 FDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLL----RFELLPDPTRVPM 488

  Fly   478 KIVVKNILISAENGIHLKVEKL 499
            .:.  .:::.::|||:|.::||
Mouse   489 PLA--RLVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	117/466 (25%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	120/483 (25%)