Protein Alignment Cyp6a17 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 503
• Identity: 170/503 - (33%)
• Similarity: 270/503 - (53%)
• Gaps: 30/503 - (5%)

  Fly     2 LLLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNSD 66
            :|||..:|:|.|.   ....||.:::.|||..:..|..|.|..:  ::...|.....:.||..
Mouse    13 MLLATSLVLLYLY---GTHSHGIFKKLGIPGPKPLPFLGTILAY--QKGFWECDIQCHKKYGK-- 70

  Fly    67 YPFAGFFFFFTRTAVVTDMELLKRVLIKD-FNHFENRGVFYNEIDDP---LSATLFSIEGQKWRH 127
              ..|.:........:||.:::|.||:|: ::.|.||..|     .|   |...:...|.::|:.
Mouse    71 --MWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRF-----GPVGILKKAISISENEEWKR 128

  Fly   128 LRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRS-KTAADRGQVLEVVDLVARYTADVIGNCAFG 191
            :|..|:||||||::|.||||   :.:..|.:.|: :.....|:...:.|:...|:.|||...:||
Mouse   129 IRALLSPTFTSGRLKEMFPI---INQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSMDVITATSFG 190

  Fly   192 LNCNSLYDPKAEFVSIGKRAITEHRYGNM-LDIFLFGF-PKLSRRLRLKLNIQEAEDFYTKIVRE 254
            :|.:||.:|:..||...|:.:....:..: |.:.||.| ..:...|.:.|..::...|:|..|..
Mouse   191 VNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDALNVSLFPRDVISFFTTSVER 255

  Fly   255 TIDYRLRTKEK-RNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALY 318
            ..:.|::.||| |.||:..:|.. :|.::..|...|:..|::||:.||..||:||:|:.:.||||
Mouse   256 MKENRMKEKEKQRVDFLQLMINS-QNYKTKESHKALSDVEIVAQSVIFIFAGYETTSSALSFALY 319

  Fly   319 ELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSP 383
            .||.:.|||.||::||.... .:....||:.:.:|:||:.||.||||.||:...|.|:..||.
Mouse   320 LLAIHPDVQKKLQDEIDAAL-PNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDV-- 381

  Fly   384 EDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLR 448
            |....||.|||:|:||...:|.||..:||||.|:||||:.:...:.....:||||.|||||||:|
Mouse   382 EINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYMYLPFGSGPRNCIGMR 446

  Fly   449 FGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGIHLKV 496
            |.::...|.|..:::.:......||:||:|: .|..|:..||.:.|||
Mouse   447 FALINMKVALVRVLQNFTVQPCKETEIPLKL-SKQGLLQPENPLLLKV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	150/434 (35%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	152/441 (34%)