Protein Alignment Cyp6a17 and CYP4F22

DIOPT Version :10

• Sequence 1: NP_652018.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 110/413 - (26%)
• Similarity: 198/413 - (47%)
• Gaps: 33/413 - (7%)

  Fly   104 VFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRG 168
            :||..:...|...|...:|.||...|..|||.|....:|....|..:..:.|...:| ..|....
Human   131 LFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWR-HLAEGSA 194

  Fly   169 QVLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVS--IGKRAIT---EHRYGNMLDIFLFGF 228
            ..|::.:.::..|.|.:..|.|..|.| ..:..::::|  |...|::   ::|..:.|| |::..
Human   195 VSLDMFEHISLMTLDSLQKCVFSYNSN-CQEKMSDYISAIIELSALSVRRQYRLHHYLD-FIYYR 257

  Fly   229 PKLSRRLRLKLNIQEAEDFYTKIVRET--------IDYRLRTKE-KRNDFMDSLIEMYKNEQSGN 284
            ....||.|...::  ...|.|::::|.        .:..|:.|: |..||:|.|:       ...
Human   258 SADGRRFRQACDM--VHHFTTEVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLL-------LAR 313

  Fly   285 SEDG--LTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVF-GKHNKEFT 346
            .|||  |:..::.|:|..|...|.:|:|:.:.:.|:.||:..:.|:|.||||..|. |:..:|..
Human   314 DEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378

  Fly   347 YEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYP 411
            ::.:.::.:....:.|:||:||.:..::|....|....|.: .|.||.|.::...|.|::|.::|
Human   379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR-IIPKGIICLVSIYGTHHNPTVWP 442

  Fly   412 EPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIP 476
            :.:::.|.||..:....|....::||..|||||||..|.|.:..|.:|..:..::.||....::.
Human   443 DSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVR 507

  Fly   477 MKIVVKNILISAENGIHLKVEKL 499
            .|   ..:::..|||:.||||.|
Human   508 RK---PELILRTENGLWLKVEPL 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_652018.1	CYP6-like	66..493	CDD:410679	105/405 (26%)
CYP4F22	NP_775754.2	CYP4F	82..523	CDD:410772	105/407 (26%)