Protein Alignment Cyp6a17 and CYP4F8

DIOPT Version :9

• Sequence 1: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 113/415 - (27%)
• Similarity: 194/415 - (46%)
• Gaps: 37/415 - (8%)

  Fly   104 VFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRG 168
            |||..:...|...|....|.||||.|..|||.|....:|....|..|....|...:: :.|.:..
Human   123 VFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQ-RLAMEGS 186

  Fly   169 QVLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVS--------IGKRAITEHRYGNMLDIFL 225
            ..|:|.:.::..|.|.:..|.|..:.|....| :|:::        :.||.....||.:    ||
Human   187 TCLDVFEHISLMTLDSLQKCIFSFDSNCQEKP-SEYITAIMELSALVVKRNNQFFRYKD----FL 246

  Fly   226 FGFPKLSRRLRLKLNIQEAEDFYTKIVRET--------ID--YRLRTKEKRNDFMDSLIEMYKNE 280
            :......||......:  ..||...:::|.        :|  .:.:.|.|..||:|.|:   .:|
Human   247 YFLTPCGRRFHRACRL--VHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLL---LSE 306

  Fly   281 QSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVF-GKHNKE 344
            .....|  |:..::.|:|..|...|.:|:::.:.:.||.|||:.:.|::.|:|:..:. .:..||
Human   307 DKNGKE--LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKE 369

  Fly   345 FTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDI 409
            ..::.:.::.:|...:.|:||.:|.:....|....|....|.: .|.||.:..|....||::|.:
Human   370 IEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSR-VIPKGNVCNINIFAIHHNPSV 433

  Fly   410 YPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQ 474
            :|:||::.|.||..|....|....::||..|||||||.:|.|.:..|.||..:  .:|.:.|:.:
Human   434 WPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTL--LRFRILPDHR 496

  Fly   475 IPMKIVVKNILISAENGIHLKVEKL 499
            .|.:  ...|::.||:|:.|:||.|
Human   497 EPRR--TPEIVLRAEDGLWLRVEPL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	105/392 (27%)
CYP4F8	NP_009184.1	p450	52..504	CDD:306555	105/398 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810