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Protein Alignment eIF4E1 and Eif4e3

DIOPT Version :9

Sequence 1:	NP_001261626.1	Gene:	eIF4E1 / 45525	FlyBaseID:	FBgn0015218	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_080105.1	Gene:	Eif4e3 / 66892	MGIID:	1914142	Length:	207	Species:	Mus musculus

Alignment Length:	235	Identity:	65/235 - (27%)
Similarity:	104/235 - (44%)	Gaps:	44/235 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 PPTSAAAPAEAKDVKPKEDPQETGEPAGNTATTTAPAGDDAVRTEHLYKHPLMNVWTLWYLENDR 96
            ||  ||||..|.:...|.......||.|                     .||.:.||.|.   ||
Mouse     4 PP--AAAPPGANEPLDKALSALPPEPGG---------------------VPLHSPWTFWL---DR 42

  Fly    97 S----KSWEDMQN--EITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGG 155
            |    .:.|...|  :|.:..||:.|||:||:|.|.:.:.|...|.|.:...||:||:.:|.:||
Mouse    43 SLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGG 107

  Fly   156 RWVITLNKSSKTDLDNLWLDVLLCLIGEAFDH----SDQICGAVINIRGKSNKISIWTADGN--N 214
            .|.:.:.|.|.:   .:|.::||..|||.|..    .|:|.|..:::|.:.:.:.:|..:.:  .
Mouse   108 VWKMKVPKDSTS---TVWKELLLATIGEQFTDCAAADDEIIGVSVSVRDREDVVQVWNVNASLVG 169

  Fly   215 EEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVK 254
            |...||..|:|...:..   .::.|:.|::....:|...|
Mouse   170 EATVLEKIHQLLPHIAF---KAVFYKPHEEHHAFEGGRGK 206

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.