Protein Alignment eIF4E1 and Eif4e3

DIOPT Version :10

• Sequence 1: NP_524829.1
• Gene: eIF4E1 / 45525
• FlyBaseID: FBgn0015218
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_080105.1
• Gene: Eif4e3 / 66892
• MGIID: 1914142
• Length: 207
• Species: Mus musculus
• Alignment Length: 235
• Identity: 65/235 - (27%)
• Similarity: 104/235 - (44%)
• Gaps: 44/235 - (18%)

  Fly    32 PPTSAAAPAEAKDVKPKEDPQETGEPAGNTATTTAPAGDDAVRTEHLYKHPLMNVWTLWYLENDR 96
            ||  ||||..|.:...|.......||.|                     .||.:.||.|.   ||
Mouse     4 PP--AAAPPGANEPLDKALSALPPEPGG---------------------VPLHSPWTFWL---DR 42

  Fly    97 S----KSWEDMQN--EITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGG 155
            |    .:.|...|  :|.:..||:.|||:||:|.|.:.:.|...|.|.:...||:||:.:|.:||
Mouse    43 SLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGG 107

  Fly   156 RWVITLNKSSKTDLDNLWLDVLLCLIGEAFDH----SDQICGAVINIRGKSNKISIWTADGN--N 214
            .|.:.:.|.|.:   .:|.::||..|||.|..    .|:|.|..:::|.:.:.:.:|..:.:  .
Mouse   108 VWKMKVPKDSTS---TVWKELLLATIGEQFTDCAAADDEIIGVSVSVRDREDVVQVWNVNASLVG 169

  Fly   215 EEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVK 254
            |...||..|:|...:..   .::.|:.|::....:|...|
Mouse   170 EATVLEKIHQLLPHIAF---KAVFYKPHEEHHAFEGGRGK 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E1	NP_524829.1	IF4E	82..239	CDD:460281	50/168 (30%)
Eif4e3	NP_080105.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		8/21 (38%)
		IF4E	31..181	CDD:460281	49/155 (32%)