Protein Alignment eIF4E1 and eIF4E4

DIOPT Version :9

• Sequence 1: NP_001261626.1
• Gene: eIF4E1 / 45525
• FlyBaseID: FBgn0015218
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_648052.1
• Gene: eIF4E4 / 38743
• FlyBaseID: FBgn0035709
• Length: 229
• Species: Drosophila melanogaster
• Alignment Length: 178
• Identity: 133/178 - (74%)
• Similarity: 154/178 - (86%)
• Gaps: 1/178 - (0%)

  Fly    80 KHPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRP 144
            ||||.|.||||||||||||:||||||||||||.||||||||||||.||||::|||||||||.|:|
  Fly    51 KHPLENTWTLWYLENDRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQP 115

  Fly   145 MWEDAANKQGGRWVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWT 209
            ||||.|||.||||||.:.:.||.:||.|||||||.||||||::::::||||||:|||||||||||
  Fly   116 MWEDDANKFGGRWVINMGRGSKAELDKLWLDVLLILIGEAFENTEEVCGAVINLRGKSNKISIWT 180

  Fly   210 ADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIY 257
            |:|:||.|.:|||.||||.|.| ..:.||||||||||.||||.:|::|
  Fly   181 ANGHNELAVMEIGLKLRDLLVL-PPHQLQYQLHKDTMCKQGSVIKAVY 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E1	NP_001261626.1	IF4E	82..239	CDD:366742	116/156 (74%)
eIF4E4	NP_648052.1	IF4E	56..209	CDD:279921	114/153 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470281
Domainoid	1	1.000	143	1.000	Domainoid score	I1494
eggNOG	1	0.900	-	-		E1_COG5053
Homologene	1	1.000	-	-		H123817
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1633
Isobase	1	0.950	-	0	Normalized mean entropy	S964
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	1	1.000	-	-		FOG0000666
OrthoInspector	1	1.000	-	-		mtm6577
orthoMCL	1	0.900	-	-		OOG6_100627
Panther	1	1.100	-	-	P	PTHR11960
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R595
SonicParanoid	1	1.000	-	-		X406
	14	13.780