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Protein Alignment eIF4E1 and Eif4e

DIOPT Version :9

Sequence 1:	NP_001261626.1	Gene:	eIF4E1 / 45525	FlyBaseID:	FBgn0015218	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_446426.1	Gene:	Eif4e / 117045	RGDID:	69647	Length:	217	Species:	Rattus norvegicus

Alignment Length:	233	Identity:	108/233 - (46%)
Similarity:	139/233 - (59%)	Gaps:	24/233 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PE-PPTSAAAPAEAKDVKPKEDPQETGEPAGNTATTTAPAGDDAVRTEHLYKHPLMNVWTLWYLE 93
            || .||:...|||.:..   |..||...|                  ||..||||.|.|.||:.:
  Rat     6 PETTPTTNPPPAEEEKT---ESNQEVANP------------------EHYIKHPLQNRWALWFFK 49

  Fly    94 NDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWV 158
            ||:||:|:.....|:.||||||||:|||||:..|.:..|.||||||..|.|||||..||:||||:
  Rat    50 NDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWL 114

  Fly   159 ITLNKSS-KTDLDNLWLDVLLCLIGEAF-DHSDQICGAVINIRGKSNKISIWTADGNNEEAALEI 221
            |||||.. ::|||..||:.|||||||:| |:||.:||||:|:|.|.:||:|||.:..|.:|...|
  Rat   115 ITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHI 179

  Fly   222 GHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 259
            |...::.|.|.....:.||.|.||..|.||..|:.:.:
  Rat   180 GRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.