DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p1 and CYP96A4

DIOPT Version :9

Sequence 1:	NP_524828.1	Gene:	Cyp4p1 / 45524	FlyBaseID:	FBgn0015037	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_200045.1	Gene:	CYP96A4 / 835308	AraportID:	AT5G52320	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	122/541 - (22%)
Similarity:	213/541 - (39%)	Gaps:	102/541 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIILWLILA-LSALLYWLHRANKDYHILSFFTKRIRLKDGTPVEIIAPIAKGKTIFGNTLDLYGR 64
            |::.|.:|. |..:|:.:.|      |..|.|:.:..::.|.. .|.|...|..|. .|:|...
plant    33 MVMNWPVLGMLPGVLFQIPR------IYDFVTEALEAENMTGC-FIGPWLSGTDIL-LTVDPVN- 88

  Fly    65 DHAGVFNYSRERAKEMGTSYIEYVFGKAIYNIIDADSAENVLNHPNLITKGLVYNFLHPFLRTGL 129
                                |:|:.            :.|.:|:|    ||..:|.:..||..|:
plant    89 --------------------IQYIL------------SSNFVNYP----KGKKFNKIFEFLGDGI 117

  Fly   130 LTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKF------LLQFEGQDEVTITLHDVIPRF 188
            .......|...|......|.......|.  ..|...|.      :|....:..:.:.|.|:..||
plant   118 FNVDSGLWEDMRNSSHAIFSHQDFQSFS--VSTSVSKLSQGLVPILDNAVEKHILVDLQDLFQRF 180

  Fly   189 TLNSICETAMG-------VKLD--EMAEKGDRYRENFSQIEECFIRRLSNPLLWG-DKLFEMFAA 243
            ..::......|       |::.  |.|:..|      ...:..|.|.|....||. .....:...
plant   181 LFDTSSTLMAGYDPKSLSVEMPKVEFADAMD------GVADAMFYRHLKPAFLWSIQSWIGVGIE 239

  Fly   244 KDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDGFVSKKRFAM--------LDTLIYAE 300
            |.....|||..:...:||:.:|:.:|:.           |....|..||        :||..|..
plant   240 KKMRRGLDVFDQMLGKIISAKREEIKNH-----------GIHDSKGEAMDVLTYYMTIDTTKYKH 293

  Fly   301 KDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSNLDVGQ 365
            .....|.. |.:.:..|:....||||..|.:....:|.||:    ...:|::.|:..:...|...
plant   294 LKPSNDKF-IRDTILGLVIAARDTTSSALTWFFWLLSKNPE----AMTKIRQEINKKMPKFDPAD 353

  Fly   366 LNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYW-DSPE 429
            |:||.||:..:.||.||:||||...:...:...|.:|..:.|..::.|.::.:.|....| |..|
plant   354 LDKLVYLDGAVCETLRLYPSVPFNHKSPAKPDVLPSGHKVDKNWRVVIPIYSLGRMKSVWGDDAE 418

  Fly   430 EFRPERFLPEN--VQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQF--KVLKAIDPQK 490
            :|||||::.::  ::...:|.::.|:||.|.|:||:....:|||:.|.:::.:  ||::...|:.
plant   419 DFRPERWISDSGMLRQESSYKFLAFNAGPRTCLGKRLTFLQMKTVAVEIIRNYDIKVVEGHKPKP 483

  Fly   491 IVFHTGITLRTQDKIRVKLVR 511
            :   ..:.||.|..::|.:.:
plant   484 V---PSVLLRMQHGLKVSVTK 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	109/483 (23%)
CYP96A4	NP_200045.1	p450	1..501	CDD:416425	122/539 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920