DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4p1 and CYP86C2

DIOPT Version :9

Sequence 1:	NP_524828.1	Gene:	Cyp4p1 / 45524	FlyBaseID:	FBgn0015037	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_189243.1	Gene:	CYP86C2 / 822212	AraportID:	AT3G26125	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	121/528 - (22%)
Similarity:	224/528 - (42%)	Gaps:	91/528 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 GTPVEIIAPIAKGKTIFGNTLDLYGRDHAGVFNY-SRERAKEMGTSYIEYVFGKAIYNIIDADSA 102
            |.||:        ..:||.|.:.:...| .:|.: :|...|..||...:.::....|..:.:..|
plant    44 GEPVQ--------WPVFGITPEFFLHVH-DMFGWVTRCLTKSRGTFPYQGIWFSGSYGAMTSVPA 99

  Fly   103 E-------NVLNHPNLITKGLVY-NFLHPFLRTGLLTSTGKKWHARRKMLTPTFHFN--ILNQFQ 157
            .       |..|.|    ||..| ......|..|:..:..:.|..:|:::....|..  :.:.||
plant   100 NIEYMLKTNFKNFP----KGEFYKERFRDLLEDGIFNADDESWKEQRRIIITEMHSTRFVDHSFQ 160

  Fly   158 ---EIFKTESQKFLLQFEGQDEVTITLHDVIPRFTLNSICETAMGVKLDEMAEKGD-----RYRE 214
               ::.:.:..|.:..|....| ...|.:::.|.|.::||...:|   |:.....|     .:.:
plant   161 TTRDLIERKLLKVMESFSKSQE-AFDLQEILLRLTFDNICIAGLG---DDPGTLDDDLPHVPFAK 221

  Fly   215 NFSQ-IEECFIRRLSNPLLWGD-KLFEMFAAKDFASALDVVHRFSSEIIAKRRDLLKDELDKSSS 277
            .|.: .|....|.:..|.:|.. |.|::...|....|::.||.|..:::.:|..:|||:...::|
plant   222 AFEEATESTLFRFMIPPFVWKPMKFFDIGYEKGLREAVETVHNFIDKMVVERIAMLKDQGTLANS 286

  Fly   278 TADDDGFVSKKRFAMLDTLIYAE--KDGLIDHIGICEEVD------------TLMFEGYDTTSIG 328
            .:|           :|..||..|  |.|        :|.|            :.:..|.||:|:.
plant   287 KSD-----------VLSRLIQIESHKRG--------DENDRFTAKFFRQFCTSFILAGRDTSSVA 332

  Fly   329 LIFGLMNMSLNPDKQELCYQEIQEHIDDDLSN---LD------------VGQLNKLKYLEYFMKE 378
            |.:....::.:|:.:.....||:|.::....|   ||            |.:||.:.||:..:.|
plant   333 LTWFFWLITKHPEVETKILHEIREILNQREKNKYKLDETGEKESSRHFTVKELNDMVYLQAALSE 397

  Fly   379 TTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYWDSP-EEFRPERFLP--EN 440
            :.||:|.:|:..::|.:|....:|..|.||:::...|:.:.|....|... |.|:|||::.  :.
plant   398 SLRLYPPIPMEMKQATEEDVFPDGTFLRKGSRVYFSVYAMGRMESIWGKDCEMFKPERWIQGGQY 462

  Fly   441 VQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDPQKIVFHTGITLRTQDKI 505
            |.| ..:.||.|:||.|.|:||.:|..:||.:...:|..:.: |......:|.....||..:..:
plant   463 VSD-DQFKYVVFNAGPRLCLGKTFAYLQMKMVAASILLNYSI-KVDQDHVVVPRVTTTLYMKHGL 525

  Fly   506 RVKLVRRT 513
            :|::..|:
plant   526 KVRITPRS 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	117/507 (23%)
CYP86C2	NP_189243.1	PLN03195	42..533	CDD:215627	120/526 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910