DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p1 and CYP94B2

DIOPT Version :9

Sequence 1:	NP_524828.1	Gene:	Cyp4p1 / 45524	FlyBaseID:	FBgn0015037	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_566155.1	Gene:	CYP94B2 / 821263	AraportID:	AT3G01900	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	126/549 - (22%)
Similarity:	223/549 - (40%)	Gaps:	106/549 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIILWLILALSALLYWLHRAN-KDYHI----LSFFTKRIRLKDGTPVEIIAPIAKGKTIFGNTLD 60
            :::|.|:.|...::|....:. |.|.:    :||:|.|.||.|.. .|::.. :..:|:....|
plant    11 VLVLLLVSAGKHVIYSCRNSTPKTYPVIGCLISFYTNRNRLLDWY-TELLTE-SPSRTVVIRRL- 72

  Fly    61 LYGRDHAGVFNYSRERAKEMGTSYIEYVFGKAIYNIIDADSAENVLNHPNLITKGLVY-NFLHPF 124
                       .:|........|.:||:.            ..|..|:|    ||..: ..|..|
plant    73 -----------AARRTVVTANPSNVEYIL------------KTNFDNYP----KGKPFTEILGDF 110

  Fly   125 LRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQF---EGQDEVTITLHDVIP 186
            |..|:....|..|..:|::.|..|....|.::..:.:.|.:|.||.|   ..:|.....|.:::.
plant   111 LGNGIFNVDGNLWLKQRRLATHDFTPKSLREYVTVLRNEVEKELLAFLNAAAEDSQPFDLQELLR 175

  Fly   187 RFTLNSICETAMGVKLDEMAEKGDRYREN----FSQIEECF-------IRRLSNPL--LWGDKLF 238
            |||.|.:|...:|:         ||...|    .|:.:..|       ..|.|.||  :|..|..
plant   176 RFTFNIVCIVFLGI---------DRCTLNPSSPVSEFDRAFQTASAVSAGRGSAPLSFVWKFKRL 231

  Fly   239 EMFAA-KDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDGFVSKKRFAMLDTLIYAEKD 302
            ..|.: |:...|:..||....|||.          ||....|:.| |:|:       .::..|.|
plant   232 VGFGSEKELRKAVGEVHNCVDEIIR----------DKKRKPANQD-FLSR-------LIVAGESD 278

  Fly   303 GLIDHIGICEEVDTLMFEGYDTTS------IGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSNL 361
            ..:.     :.|.:::..|.||||      ..||.|      :.:.:.....||:...::.....
plant   279 ETVR-----DMVISIIMAGRDTTSAVATRLFWLITG------HEETEHDLVSEIRSVKEEITGGF 332

  Fly   362 DVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYW- 425
            |...|.||..|:..:.|..||:|.||...:.|:.:..|.:|.::..|.::|...:.:.|..:.|
plant   333 DYESLKKLSLLKACLCEVMRLYPPVPWDSKHALTDDRLPDGTLVRAGDRVTYFPYGMGRMEELWG 397

  Fly   426 DSPEEFRPERFLPEN-------VQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVL 483
            :..:||:|.|:....       ::..:.:.:..|.||.|.|:|::.|..:||.::..:|.:|::
plant   398 EDWDEFKPNRWAESYDKTCCRVLKKVNPFKFPVFQAGPRVCLGEEMAYVQMKYIVASILDRFEI- 461

  Fly   484 KAIDPQKIVFHTGITLRTQDKIRVKLVRR 512
            :.|...|..|...:|......::|::.||
plant   462 EPIPTDKPDFVPMLTAHMAGGMQVRVHRR 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	109/486 (22%)
CYP94B2	NP_566155.1	CYP86A	65..483	CDD:410687	109/484 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010