DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4p1 and BAS1

DIOPT Version :9

Sequence 1:	NP_524828.1	Gene:	Cyp4p1 / 45524	FlyBaseID:	FBgn0015037	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	131/550 - (23%)
Similarity:	217/550 - (39%)	Gaps:	118/550 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIILWLILAL-----SALLYWLHRANKDYHILSFFTKR-IRLKDGTPVEIIAPIAKGKTIFGNTL 59
            :::|.:||:|     .:||:|..|..:::     |:|: ||   |.|...         ..||..
plant    13 VLVLSVILSLVIVKGMSLLWWRPRKIEEH-----FSKQGIR---GPPYHF---------FIGNVK 60

  Fly    60 DLYG-----RDHAGVFNYS---------RERAKEMGTSYIEYVFGKAI-YNIIDADSAENVLNHP 109
            :|.|     ..|...|:::         ....|..|.:::.: ||... ..:.|.|....:.:..
plant    61 ELVGMMLKASSHPMPFSHNILPRVLSFYHHWRKIYGATFLVW-FGPTFRLTVADPDLIREIFSKS 124

  Fly   110 NLITKGLVYNFLHPFLR----TGLLTSTGKKWHARRKMLTPTFHFN--------ILNQFQEIFKT 162
            ....|    |..||.::    .|||:..|:||...||:::||||..        :|....::...
plant   125 EFYEK----NEAHPLVKQLEGDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDK 185

  Fly   163 ESQKFLLQFEGQDEV------TITLHDVIPRFTLNSICETAMGV---KLDEMAEKGDRYRENFSQ 218
            .|.|  |...|:.||      .|...|||.|....|..|....|   :..:|....:.:::.|..
plant   186 WSDK--LSENGEVEVDVYEWFQILTEDVISRTAFGSSYEDGRAVFRLQAQQMLLCAEAFQKVFIP 248

  Fly   219 IEECFIRRLSNPLLWGDKLFEMFAAKDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDG 283
            ....|..| .|...|                     :...||   |:.|||....:..:..|.:|
plant   249 GYRFFPTR-GNLKSW---------------------KLDKEI---RKSLLKLIERRRQNAIDGEG 288

  Fly   284 FVSKKRFA--MLDTLIYAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELC 346
            ...|:..|  :|..:|.|:...:.|   |.||..:..|.|..|||..|.:..:.:|::|:.|...
plant   289 EECKEPAAKDLLGLMIQAKNVTVQD---IVEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKA 350

  Fly   347 YQEIQEHIDD-DLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQ 410
            ..|:...... |:...|  .:.|||.|...:.|:.||:|.:....|.|..:.:| .|..:|.|.:
plant   351 RDEVLRVCGSRDVPTKD--HVVKLKTLSMILNESLRLYPPIVATIRRAKSDVKL-GGYKIPCGTE 412

  Fly   411 ITIHVFDIHRNAKYW-DSPEEFRPERF---LPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKT 471
            :.|.:..:|.:...| :...||.|.||   :|...  :|...::||..|.|.|||:..|:.:.|.
plant   413 LLIPIIAVHHDQAIWGNDVNEFNPARFADGVPRAA--KHPVGFIPFGLGVRTCIGQNLAILQAKL 475

  Fly   472 LMVVLLKQF------------KVLKAIDPQ 489
            .:.|::::|            .||..:.||
plant   476 TLAVMIQRFTFHLAPTYQHAPTVLMLLYPQ 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	116/490 (24%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	110/460 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960