DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p1 and cyp2j20

DIOPT Version :9

Sequence 1:	NP_524828.1	Gene:	Cyp4p1 / 45524	FlyBaseID:	FBgn0015037	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	XP_001337781.3	Gene:	cyp2j20 / 797309	ZFINID:	ZDB-GENE-041210-324	Length:	496	Species:	Danio rerio

Alignment Length:	511	Identity:	119/511 - (23%)
Similarity:	189/511 - (36%)	Gaps:	126/511 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ILSFFTKRIRLKDGTPVEIIAPIAKGKTIFGNTLDLYGRDHAGVFNYSRERAKEMGTSYIEYVFG 90
            :||.|.|....|:..|.....||..         |::..|.:.:.....|.|::.|..:...:||
Zfish    24 LLSDFIKNKTPKNFPPGPWSLPIIG---------DIHHIDPSKLHLQLSEFAEKYGKIFSLRLFG 79

  Fly    91 KAI-----YNIID----------ADSAENVLNHPNLITKGLVYNFLHPFLRTGLLTSTGKKWHAR 140
            ..|     ||::.          ||.|...|.|..:..||||             .|:|.||..:
Zfish    80 PRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDIIGDKGLV-------------ASSGYKWKQQ 131

  Fly   141 RKMLTPTFH------------FNILNQF--QEIFKTESQKFLLQFEGQDEVTITLHDVIPRFTLN 191
            |:....|..            .|:.:.|  :.|...:.|.|                 .||..||
Zfish   132 RRFALSTLRNFGLGKKNLEPSINLESGFLNEAISNEQGQPF-----------------DPRLLLN 179

  Fly   192 S-----ICETAMGVKLDEMAEKGDRYRENFSQ---IEECFIRRLSNPL----------------L 232
            :     ||....|.:.|....|.....:|.::   :|.....:|.|.|                |
Zfish   180 NAVSNVICALVFGNRFDYSDHKFQTLLKNINETVHLEGGICAQLYNMLPWLMRLLPGPHKRIIAL 244

  Fly   233 WGDKLFEMFAAKDFASALDVVHRFSSEIIAKRR--DLLKDELDKSSSTADDDGFVSKKRFAMLDT 295
            || ||.|....|...      |:...:.:..|.  |...||::|..   ||..       |..|
Zfish   245 WG-KLIEFVGEKVNE------HKVDHDPLNPRDYIDCFLDEMEKHK---DDTA-------AGFD- 291

  Fly   296 LIYAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSN 360
                     ::::.|| .:| |...|.:|||..|.:||:.|...|:.|....||| :.|......
Zfish   292 ---------VENLCIC-TLD-LFVAGTETTSTTLYWGLLYMMKYPEIQAKVQQEI-DVIVGGSRQ 344

  Fly   361 LDVGQLNKLKYLEYFMKETTRLFPSVPI-MGREAVQETELANGLILPKGAQITIHVFDIHRNAKY 424
            ..|...:.:.|....:.|..|:...:|| :.|...::|::.. ..:|||..:|.::..:..:...
Zfish   345 PSVSDRDNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEK-YSIPKGTMVTSNLTSVLFDESE 408

  Fly   425 WDSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQF 480
            |::|..|.|..||....:.|...|::|||.|:|.|:|::.|..|:......||::|
Zfish   409 WETPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRF 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	111/483 (23%)
cyp2j20	XP_001337781.3	p450	38..492	CDD:278495	114/497 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010