DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p1 and Cyp4f37

DIOPT Version :9

Sequence 1:	NP_524828.1	Gene:	Cyp4p1 / 45524	FlyBaseID:	FBgn0015037	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001093657.1	Gene:	Cyp4f37 / 677156	MGIID:	3780112	Length:	546	Species:	Mus musculus

Alignment Length:	448	Identity:	140/448 - (31%)
Similarity:	213/448 - (47%)	Gaps:	48/448 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 HAGVFNYSRERAK---EMGTSYIEY---VFGKAI--YNIIDADSAENVLNHPNLITKGLV----- 117
            |.|:..::.|..:   |.|.:|.:.   ..|..|  ..|:|.     ....|.|:...||
Mouse    63 HLGMIEHNEEGMQLMTEAGQTYRDVHLCWLGPVIPVLRIVDP-----AFVAPLLLASALVAPKDT 122

  Fly   118 --YNFLHPFLRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFL------LQFEGQ 174
              :.|:.|:|..||..::|.||...|::|||.|||:||..:.:|| .:|...:      |..||.
Mouse   123 TFHTFVKPWLGDGLFLNSGDKWSRHRRLLTPAFHFDILKPYVKIF-NQSVNIMHAKWKHLSSEGS 186

  Fly   175 DEVTITLHDVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFE 239
            ..:.:..|  |...||:|:.:...|.. ....|....|.....::....|:|.....|:.|.|:.
Mouse   187 ARLEMFEH--ISLMTLDSLQKCLFGFD-SNCQESPSEYISAILELSSLVIKRSHQLFLFVDFLYY 248

  Fly   240 MFA-AKDFASALDVVHRFSSEIIAKRRDLLK----DELDKSSSTADDDGFVSKKRFAMLDTLIYA 299
            ..| .:.|..|.|:||.|:..:|.:||..|.    ||..||.:        ..|....:|.|:.|
Mouse   249 HTADGRRFRKACDLVHNFTDAVIRERRHTLSSQNHDEFLKSKT--------KSKTLDFIDVLLLA 305

  Fly   300 EKD---GLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHI-DDDLSN 360
            :.:   .|.|. .|..|.||.||.|:|||:..|.:.|.|::.:|:.||.|.||:||.: ..:...
Mouse   306 KDEHGKELSDE-DIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQE 369

  Fly   361 LDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYW 425
            ::...|.:|.:|...:||:.||.|.|..:.|...::..|.:|.::|||....|.:|.||.|...|
Mouse   370 IEWDDLAQLPFLTMCIKESLRLHPPVIDLLRRCTRDIVLPDGRVIPKGNICVISIFGIHHNPSVW 434

  Fly   426 DSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVL 483
            ..||.:.|.||.|||...|...|::|||||.|||||:.:||.||...:.:.|.:|::|
Mouse   435 PDPEVYDPFRFDPENAHKRPPLAFIPFSAGPRNCIGQTFAMNEMMVALALTLLRFRIL 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	140/448 (31%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	137/437 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845314
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840