Protein Alignment Cyp4p1 and cyp46a1.1

DIOPT Version :10

• Sequence 1: NP_524828.1
• Gene: Cyp4p1 / 45524
• FlyBaseID: FBgn0015037
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001018358.1
• Gene: cyp46a1.1 / 553543
• ZFINID: ZDB-GENE-050522-464
• Length: 501
• Species: Danio rerio
• Alignment Length: 524
• Identity: 120/524 - (22%)
• Similarity: 224/524 - (42%)
• Gaps: 104/524 - (19%)

  Fly     3 ILWLILALSALLY--------WLHRANKDY-HILSFFTKRIRLKDGTPVEIIAPIAKGKTIFGNT 58
            :|:::..|.|.::        ::|..::.| ||           .|.|        :...:.|::
Zfish     6 VLYIVFFLLAAVFTAFLGYCLYIHHLHQKYDHI-----------PGPP--------RDSFLLGHS 51

  Fly    59 LDL----YGRDHAGVFNYSRERAKEMGTSY----IEYVFGKAIYNIIDADSAENVLNHPNLITKG 115
            ..|    |. |:..:.:.....|::.|..|    :.||    ...:...::.:.::..|..|...
Zfish    52 SSLTKAVYS-DNNLIHDLFLHWAEKYGPVYRINTLHYV----TIMVYCPEATKTIMMSPKYIKDP 111

  Fly   116 LVYN-----FLHPFLRTGLLTSTG-KKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFE-- 172
            .||.     |...||..||:|:.. ..|:.:|:::.|.|....|......|...|::.:.:.|
Zfish   112 FVYKQLFNLFGKRFLGNGLITAVDHDMWYRQRRIMDPAFSSTYLRSLISTFDEMSERLMDKLEEM 176

  Fly   173 GQDEVTITLHDVIPRFTLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLL-WGDK 236
            ..::....:||::...||:.||:.|.||.|:.:.:|...::   :.:|.|    |...:| ..|.
Zfish   177 ANNKTPAVMHDLVNCVTLDVICKVAFGVDLNLLNQKDSPFQ---NAVELC----LKGMILDVRDP 234

  Fly   237 LFEMF-----AAKDFASALDVVHRFSSEIIAKRR-------DLLKDELDKSSSTADDDGFVSKKR 289
            .|.:|     ..:....|.:::.:...:.|..|:       |:.||.|.:...:|:::...:.:.
Zfish   235 FFRLFPKNWKLIQQVREATELLRKTGEKWIQNRKTAVKNGEDVPKDILTQILKSAEEENVNNTQD 299

  Fly   290 F-AMLDTLIYAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEH 353
            . .|||..:                  |....|.:||:..|.|.:|.:..||:    .|:..:..
Zfish   300 LEQMLDNFV------------------TFFIAGQETTANQLSFAIMALGRNPE----IYKRAKAE 342

  Fly   354 IDD------DLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQIT 412
            :|:      ::||.|:|   ||.||...:|||.||:|:.|...| .:.|..:.||:.:|:|..:.
Zfish   343 VDEVLGTKREISNEDLG---KLTYLSQVLKETLRLYPTAPGTNR-WLHEDIVINGIKVPRGCSVM 403

  Fly   413 IHVFDIHRNAKYWDSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLL 477
            ...:...|..|::..|.:|.||||  :....:..|.|.|||.|.|.|:|:.:|..|.|.::..||
Zfish   404 FSSYVSQRLEKFFKDPLKFDPERF--DVNAPKPYYCYYPFSLGPRTCLGQVFAQMEAKLVLAKLL 466

  Fly   478 KQFK 481
            ::|:
Zfish   467 QRFE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	CYP4	87..507	CDD:410721	104/423 (25%)
cyp46a1.1	NP_001018358.1	CYP46A1-like	66..495	CDD:410706	107/444 (24%)