DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4p1 and Cyp313a5

DIOPT Version :9

Sequence 1:	NP_524828.1	Gene:	Cyp4p1 / 45524	FlyBaseID:	FBgn0015037	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_650168.1	Gene:	Cyp313a5 / 41486	FlyBaseID:	FBgn0038005	Length:	487	Species:	Drosophila melanogaster

Alignment Length:	475	Identity:	120/475 - (25%)
Similarity:	213/475 - (44%)	Gaps:	71/475 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 FNYSRERAKEMGTSYIEYVFGKAIYNII---------DADSAENVLNHPNLITK-GLVYNFLHPF 124
            |.|.|.:.|....:.:..::||.:...|         :....|::...||...: .:|...:...
  Fly    45 FEYIRLKRKIRLRTILFKIYGKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSC 109

  Fly   125 LRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQ---KFLLQF-EGQDEVTITLHDVI 185
            |..||||.....|:.|||:|.|:|..|.:..|..:...|:.   ..|.:| :|.|   |.|...:
  Fly   110 LGLGLLTLKNNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGD---INLLPEL 171

  Fly   186 PRFTLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSN--------PLLWGDKLFEMFA 242
            .:::.....:..||   ||:..:.:  .:|.:.:|.  .:.|:|        |.|....|.::|:
  Fly   172 NKWSFKIAAQITMG---DEVRNQAN--YQNGNLLES--YKALNNLIPIGVVMPWLRNKYLGKLFS 229

  Fly   243 AKDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDGFVSKKRFAMLDTLIYAEKDGLIDH 307
                      ..:...|...:....:||.:||..|:.|     :....|::|.::...:.|.:.:
  Fly   230 ----------YEKRRLEAATQSNAFIKDIIDKKLSSTD-----NSSEPALIDRILNLVRIGELSY 279

  Fly   308 IGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHI----DDDLSNLDVGQLNK 368
            ..:..|...::|...||.||.:...|:.|::.|..|:..::|:.|..    :.:.|:.|   |.|
  Fly   280 DDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHAD---LEK 341

  Fly   369 LKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYWDSPE--EF 431
            |..|:..:.||.||.|:||::.|:.....:|:||..:|:|..:.|.:|..|||...| .|:  .|
  Fly   342 LVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIW-GPQANAF 405

  Fly   432 RPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQ--------FKVLKAIDP 488
            .|:.|||||.:.|..|:|:|||.|::.|:|.|.::...|..:..:|:.        :|.|:.||
  Fly   406 NPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRFID- 469

  Fly   489 QKIVFHTGITLRTQDKIRVK 508
                 :|.:.|..|..:.||
  Fly   470 -----NTTMKLAEQPLLAVK 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	120/475 (25%)
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	111/441 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I1949
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.960