Protein Alignment Cyp4p1 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_524828.1
• Gene: Cyp4p1 / 45524
• FlyBaseID: FBgn0015037
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 568
• Identity: 178/568 - (31%)
• Similarity: 290/568 - (51%)
• Gaps: 104/568 - (18%)

  Fly     3 ILWLILALSALLYWLHRANKDYHILSFF-TKRIRLKDGTPVEIIAPIAKGKTIFGNTLDLYGRDH 66
            :|::.|||..||.       .|..||.| .:|:..|...|        :|..:.||...: |::.
  Fly     4 VLYIFLALPLLLV-------AYLELSTFRRRRVLNKFNGP--------RGLPLMGNAHQM-GKNP 52

  Fly    67 A----GVFNYSRERAKEMGTSYIEYVFGKAIY-NIIDADS--AENVLNHPNLITKGLVYNFLHPF 124
            :    .||::..:..|:      .:||....| |::...|  .|.:|:...||||..:|...||:
  Fly    53 SEILDTVFSWWHQYGKD------NFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPW 111

  Fly   125 LRTGLLTSTGKKWHARRKMLTPTFHFNILNQFQEIFKTESQKFLLQFEGQDEVTITLHDVIPRF- 188
            |..|||||||.|||..|||:||.||||||..|.|:....|.||:...:     |:...|.|..|
  Fly   112 LGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLK-----TVAAGDNIFDFQ 171

  Fly   189 ------TLNSICETAMGVKLDEMAEKGDRYRENFSQIEECFIRRLSNPLLWGDKLFEMFAAKD-- 245
                  ||:.||:|||||.::.|..:.....:.|..:......|..:||...:.|:.:  |.|
  Fly   172 EQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRL--APDYP 234

  Fly   246 -FASALDVVHRFSSEIIAKRRDLLKDELDKS---SSTADDDGFVSKKRFAMLDTLIYAEKDGL-I 305
             ::..|..:..|::||||||     .|..||   |:.|.|:  .::|:.|.||||:.:..||. :
  Fly   235 AYSRTLKTLQDFTNEIIAKR-----IEAHKSGAVSTNAGDE--FTRKKMAFLDTLLSSTIDGRPL 292

  Fly   306 DHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSNLDVG------ 364
            :...:.|||.|.||||:|||:.|:.|.:..:|.:.|:|...::|.:|    .:.|.::|
  Fly   293 NSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQRE----VMGNSELGRDATFQ 353

  Fly   365 QLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYWDSPE 429
            :::::|||:.|:||..|::||||.:|| ..::..:.:|.::|||..:.:.:..:..|.|.:..|.
  Fly   354 EISQMKYLDLFIKEAQRVYPSVPFIGR-FTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPH 417

  Fly   430 EFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDPQKIVFH 494
            :||||||   .::....:.|||||||.|||||:|:|:.|:||::..:::.|:||.|:|  ::|..
  Fly   418 KFRPERF---ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALD--ELVSK 477

  Fly   495 TG------------------------------ITLRTQDKIRVKLVRR 512
            .|                              :||::::.:.::|..|
  Fly   478 DGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	162/511 (32%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	157/470 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460552
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	9	9.000