Protein Alignment Cyp4p1 and CYP4X1

DIOPT Version :9

• Sequence 1: NP_524828.1
• Gene: Cyp4p1 / 45524
• FlyBaseID: FBgn0015037
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_828847.1
• Gene: CYP4X1 / 260293
• HGNCID: 20244
• Length: 509
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 121/427 - (28%)
• Similarity: 214/427 - (50%)
• Gaps: 19/427 - (4%)

  Fly    91 KAIYNIIDADSAENVLNHPNLITKGLVYNFLHPFLRTGLLTSTGKKWHARRKMLTPTFHFNILNQ 155
            :|.:.|.|.|.|:.:|:..:..::.| ..|..|.|..||....|.||...|::|||.||||||..
Human    88 QAFFCIYDPDYAKTLLSRTDPKSQYL-QKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKA 151

  Fly   156 FQEIFKTESQKFLLQFE---GQDEVTITLHDVIPRFTLNSICETAMGVKLD-EMAEKGDRYRENF 216
            :.|:.....:..|.::|   ...:.::.:::.|...:|:.|.:.|...:.: :.....|.|.:..
Human   152 YIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAKAI 216

  Fly   217 SQIEECFIRRLSNPLLWGDKLFEMF-AAKDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTAD 280
            .::.:....||.:.|...|.:|::. ....|.....|:::::..||.:|:..|:       :...
Human   217 FELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQ-------AGVK 274

  Fly   281 DDGFVSKKRFAMLDTLIYA--EKDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQ 343
            .|....:|....||.::.|  |.......|.:..||.|.:..|:||.:..:.:.|..::|||:.|
Human   275 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339

  Fly   344 ELCYQEIQEHIDDDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKG 408
            |.|.:|::..:.|. |::...||.::.|....:|||.||.|:||.:.|:..:.....:|..||.|
Human   340 ERCREEVRGILGDG-SSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAG 403

  Fly   409 AQITIHVFDIHRNAKYWDSPEEFRPERFLPENVQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLM 473
            ..:.:.::.:|.|...|.:|:.|.|.||..||...||.|||:|||||.|||||:::||.|:|..:
Human   404 ITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTI 468

  Fly   474 VVLLKQFKVLKAIDPQK-IVFHTGITLRTQDKIRVKL 509
            .::|..|:|..  ||.: :.|.....|:.::.:.:.|
Human   469 ALILLHFRVTP--DPTRPLTFPNHFILKPKNGMYLHL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	120/425 (28%)
CYP4X1	NP_828847.1	p450	47..501	CDD:306555	120/423 (28%)
		heme binding region	447..460		9/12 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850