Protein Alignment Cyp4p1 and cyp-25A4

DIOPT Version :10

• Sequence 1: NP_524828.1
• Gene: Cyp4p1 / 45524
• FlyBaseID: FBgn0015037
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 114/522 - (21%)
• Similarity: 201/522 - (38%)
• Gaps: 144/522 - (27%)

  Fly    68 GVFNYSRERAKEMGTSYIEYVFGKAIYNIIDADSAENVLNHPNLITK-GLVYN------------ 119
            |..|..::|...:|            ||       :....||.|.|| |.::.
 Worm    46 GNLNIIKDRVSRLG------------YN-------DTTQWHPTLHTKYGPIFGLYCGTQLHITVS 91

  Fly   120 --------FLHPF----------------LRTGLLTST-GKKWHARRKMLTPTF--------HFN 151
                    |:..|                |...||.:| ...|...|..:.|.|        |..
 Worm    92 EEEDIKEIFIQNFSNFSDRMTPDIFGMNQLNQSLLQNTYATGWKHTRSAIAPIFSTGKMKAMHET 156

  Fly   152 ILNQ---FQEIFKTES---QKFLLQFEGQDEVTITLHDVIPR--FTLNSICETAMGVKLDEMAEK 208
            ::::   |.|:.|.:|   ||:.: ||....:::   |:|.:  |.::|.|:
 Worm   157 LVSKIDIFLEVLKEKSSSGQKWDI-FENFQSLSL---DIIGKCAFAIDSNCQ------------- 204

  Fly   209 GDRYRENFSQIEECFIRRLSNPLLWGDKLFEMFAAKDFASALDV--------------------- 252
              |.|.:...::                      |:.|..|:|:
 Worm   205 --RDRTDLFYVQ----------------------ARKFVGAVDLKKSWILPVSLILPELSWLWRF 245

  Fly   253 VHRFSSEIIAKRRDLLKDELDKSSSTADDDGFVSKKRFAMLDTLIYAEKDGLIDHIGICEEVDTL 317
            :::| |::.|....|:|..:|........:|  ......:|:.||..|..|.:....:.|.....
 Worm   246 LYKF-SDLSAAELPLVKGLVDLYDRRRAGEG--GNDSTDLLNLLIRRETIGKMTQREVIENCFAF 307

  Fly   318 MFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLSNLDVGQLNKLKYLEYFMKETTRL 382
            :..||:|||..::|....::..|..|:..|:||::..::  :.|:...::.:|||:...||:.|.
 Worm   308 LIAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKTKEN--AGLNYDSIHNMKYLDCVYKESLRF 370

  Fly   383 FPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKYWDSPEEFRPERFLPENVQDR-HT 446
            :|.................|.|.|:.:.:.:..:.||||...|:||:||:||||  ||.::: .:
 Worm   371 YPPTTHFTNRVCLNDMTIRGQIYPEDSTLKVQPYTIHRNPANWESPDEFQPERF--ENWEEKSSS 433

  Fly   447 YAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLKQFKV-LKAIDPQKIVFHTGITLRTQDKIRVKLV 510
            ..::||..|.|.|:|.::|..|.||.:..||..|:: |...||..|....|:..|.:..:|:.|.
 Worm   434 LKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELSLVPGDPPMIPETNGVIFRPRSPVRLNLK 498

  Fly   511 RR 512
            .|
 Worm   499 LR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	CYP4	87..507	CDD:410721	107/496 (22%)
cyp-25A4	NP_497779.1	CYP3A-like	73..494	CDD:410678	101/468 (22%)