Protein Alignment Cyp4p1 and CYP4B1

DIOPT Version :9

• Sequence 1: NP_524828.1
• Gene: Cyp4p1 / 45524
• FlyBaseID: FBgn0015037
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 133/445 - (29%)
• Similarity: 225/445 - (50%)
• Gaps: 50/445 - (11%)

  Fly    89 FGKAI--YNIIDADSAENVLNH-----PNLITKGLVYNFLHPFLRTGLLTSTGKKWHARRKMLTP 146
            ||:.|  .||.:.|.|:.|.:.     |:      ||:|...::..|||...|.||...||:|||
Human    85 FGQFIGFLNIYEPDYAKAVYSRGDPKAPD------VYDFFLQWIGRGLLVLEGPKWLQHRKLLTP 143

  Fly   147 TFHFNILNQFQEIFKTESQKFLL---QFEGQDEVTITLHDVIPRFTLNSICETAMGVKLDEMAEK 208
            .||:::|..:..:| |||.:.:|   :.:.::..:..:...:....||::.:...|        :
Human   144 GFHYDVLKPYVAVF-TESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFG--------R 199

  Fly   209 GD---------RYRENFSQIEECFIRRLSNPLLWGDKLFEMFA-AKDFASALDVVHRFSSEIIAK 263
            ||         .|....|.:.....:||.:.....|.::.:.. .:.|..|..|.|..:.::|.:
Human   200 GDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRE 264

  Fly   264 RRDLLKDELDKSSSTADDDGFVSKKRFAMLDTLIYA--EKDGLIDHIGICEEVDTLMFEGYDTTS 326
            |:..|:||..:..       ..:::....||.|:.|  |.|..:....:..||||.||||:|||:
Human   265 RKAALQDEKVRKK-------IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTT 322

  Fly   327 IGLIFGLMNMSLNPDKQELCYQEIQEHI-DDDLSNLDVGQLNKLKYLEYFMKETTRLFPSVPIMG 390
            .|:.:.|..|:|.|:.|..|.:|::|.: |.|....|  .|.|:.||...:||:.||:|.||.:.
Human   323 SGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWD--DLGKMTYLTMCIKESFRLYPPVPQVY 385

  Fly   391 REAVQETELANGLILPKGAQITIHVFDIHRNAKYWDSPEEFRPERFLPENVQDRHTYAYVPFSAG 455
            |:..:.....:|..||.|:.|::|::.:|||:..|..||.|...||..||...||.:|::|||||
Human   386 RQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAG 450

  Fly   456 QRNCIGKKYAMQEMKTLMVVLLKQFKVLKAIDPQKI-VFHTGITLRTQDKIRVKL 509
            .|||||:::||.|||.:..:.|.:|:.  ::||.:: :....:.||:::...:.|
Human   451 PRNCIGQQFAMSEMKVVTAMCLLRFEF--SLDPSRLPIKMPQLVLRSKNGFHLHL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4p1	NP_524828.1	p450	54..509	CDD:278495	132/443 (30%)
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	132/441 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154881
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850