DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mtd and LOC792958

DIOPT Version :9

Sequence 1:	NP_001246928.1	Gene:	mtd / 45467	FlyBaseID:	FBgn0013576	Length:	1344	Species:	Drosophila melanogaster
Sequence 2:	NP_001313526.1	Gene:	LOC792958 / 792958	-ID:	-	Length:	255	Species:	Danio rerio

Alignment Length:	300	Identity:	112/300 - (37%)
Similarity:	161/300 - (53%)	Gaps:	50/300 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1046 FSVPKNRVDELYRFINTW-VKHLYGELDEEQIKARGFELIQEDTEWTKSGTTKAGMGGGSQDGEE 1109
            :||  ..||.||.|...| .:::|..  :...|.:.|..:..|..              |..|..
Zfish     5 YSV--GEVDHLYTFFVEWSPENIYSH--KHSRKQQEFLQVHPDAL--------------SVIGSL 51

  Fly  1110 ISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYRKTSLFATGSFDLDFP 1174
            :.|...|:|:::.....|                               |:||:.::...:.|..
Zfish    52 LKDSPPENWQIVSVKQQK-------------------------------RRTSVCSSADSESDDL 85

  Fly  1175 IPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYRKMARLESPVLIVIED 1239
            :|.||..::||.|.|.|:|.||:||||:|..|.|::||:.||.:|.:|||:||.|:.|||:||.|
Zfish    86 LPVLINHSQILKELHLEQLMSHIPARAQGNQWKLVYSTAVHGTSLRTLYRQMAELDRPVLMVIRD 150

  Fly  1240 TEHNVFGALTSCSLHVSDHFYGTGESLLYKFNPSFKVFHWTGENMYFIKGNMESLSIGAGDGRFG 1304
            |:..||||.:|....||.:.|||||:.||.|:|.|:||.|||||.||::|.::||.:|.|.|.||
Zfish   151 TDGQVFGAFSSDPFRVSSYCYGTGETFLYSFSPEFQVFRWTGENSYFVRGFLDSLQMGGGGGPFG 215

  Fly  1305 LWLDGDLNQGRSQQCSTYGNEPLAPQEDFVIKTLECWAFV 1344
            ||||.||.:|.|..|:|:.|.||:...||.::.||.|:||
Zfish   216 LWLDADLYRGSSYSCNTFCNRPLSLHHDFTVQELEVWSFV 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mtd	NP_001246928.1	LysM	271..371	CDD:224306
		LysM	329..371	CDD:279777
		TLDc	1182..1344	CDD:214733	85/161 (53%)
LOC792958	NP_001313526.1	TLDc	93..255	CDD:214733	85/161 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I3738
eggNOG	1	0.900	-	-		E1_COG5142
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D384247at33208
OrthoFinder	1	1.000	-	-		FOG0001020
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100646
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R882
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750